Garlic promotes an acute reduction in blood pressure but does not increase the effect of exercise in promoting a reduction in blood pressure

Influence of food and nutritional supplements on exercise-induced hypotension in hypertensive patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

REBEC

Registry ID

RBR-8mc765g

Enrollment

Unknown

Registered

2021-09-20

Start date

2010-11-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Garlic

Interventions

Participants performed four experimental sessions randomly determined for each subject: two aerobic exercise sessions, one with prior garlic intake (AGE) and another with placebo (PL) and two other no

57177

Eligibility

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Have at least 3 months of physical exercise; should be hypertensive

Exclusion criteria

Exclusion criteria: Have practiced physical exercise before the experimental session; ingested alcoholic or caffeine-containing beverage one day before the experimental session; Do not sign the free and informed consent form; be menopause

Design outcomes

Primary

Measure	Time frame
Evaluate post-exercise hypotension in hypertensive individuals after supplementation with aged garlic extract. It is expected to find the pressure reduction after garlic supplementation, as well as the potentiation of hypotension caused by the physical exercise session. It will be checked by the method of measuring blood pressure, using a sphygmomanometer. The behavior of post-supplementation and post-exercise blood pressure was observed and compared to baseline values to detect post-exercise hypotension and its magnitude. From the verification of a statistically significant variation (p<0.05), we will have the indication that the supplementation was effective to reduce blood pressure and potentiate the hypotensive effect of exercise	—

Measure

Time frame

Evaluate post-exercise hypotension in hypertensive individuals after supplementation with aged garlic extract. It is expected to find the pressure reduction after garlic supplementation, as well as the potentiation of hypotension caused by the physical exercise session. It will be checked by the method of measuring blood pressure, using a sphygmomanometer. The behavior of post-supplementation and post-exercise blood pressure was observed and compared to baseline values to detect post-exercise hypotension and its magnitude. From the verification of a statistically significant variation (p<0.05), we will have the indication that the supplementation was effective to reduce blood pressure and potentiate the hypotensive effect of exercise

—

Secondary

Measure	Time frame
Secondary outcomes are not expected	—

Countries

Brazil

Contacts

Public ContactManoel Miranda Neto

manoelverdao@hotmail.com+55 (83) 999570177

Outcome results

None listed

Source: REBEC (via WHO ICTRP)