Respiration, artificial
Conditions
Interventions
The interventions were performed after inclusion in the study, each subject was submitted to only one intervention, with total duration of four consecutive hours for each patient.
The control group r
device
Sponsors
Alessandra Preisig
Faculdade de Medicina da Universidade Federal do Rio Grande do Sul (UFRGS)
Irmandade da Santa Casa de Misericórdia de Porto Alegre
Eligibility
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Postoperative cardiovascular surgery (valve replacement, thoracoabdominal aortic surgery and/or coronary artery bypass graft (CABG); Sternal incision and pulmonary artery catheter from surgical ward Both genders, aged between 18 and 80 years.
Exclusion criteria
Exclusion criteria: Severe chronic obstructive pulmonary disease, Previous neurological disease and inability to understand; More than 24 hours on mechanical ventilation; Surgical revision for bleeding after tracheal extubation; Emergency surgery; Swan-Ganz catheter nonfunctioning
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study hypothesis was that could improve gas exchange (oxygenation index, partial pressure of oxygen in arterial blood and arterial oxygen saturation) with the use of bilevel noninvasive ventilation. To evaluate this outcome, we collected blood samples (arterial blood gases) at four time points: baseline, one hour and three hours after the placement of the mask and one hour after stopping the intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| The analysis of hemodynamic variables was made by measuring the pulmonary artery catheter (Swan-Ganz) that was inserted into the surgical ward, via the internal jugular vein. The following variables were measured: heart rate (HR), mean arterial pressure (MAP), mean pulmonary artery pressure (MPAP), central venous pressure (CVP) and pulmonary capillary wedge pressure (PCWP). To measure the cardiac output (CO), 10ml of saline (0.9%) were injected manually at room temperature and was calculated by the thermodilution curve. All measurements were repeated 4-5 times, excluding outliers and held an average of three measurements. Indirect variables obtained: cardiac index (CI), systolic volume index (SVI), left ventricular stroke work index (LVSWI), right ventricle stroke work index (RVSWI), systemic vascular resistance index (SVRI) and pulmonary vascular resistance index (PVRI). | — |
Countries
Brazil
Contacts
Public ContactAlessandra Werlang
Irmandade da Santa Casa de Misericórdia de Porto Alegre
Outcome results
None listed