Infant Premature
Conditions
Interventions
Patients will be randomized into two intervention groups: the Spontaneous Breathing Test group (TRE) for 10 minutes (n=30) and the TRE group for 20 minutes (n=30).
The TRE group will consist of NBs el
Sponsors
Real Hospital Português de Beneficência em Pernambuco (RHP)
Real Hospital Português de Beneficência em Pernambuco (RHP)
Eligibility
Age
27 Weeks to 37 Weeks
Inclusion criteria
Inclusion criteria: Preterm newborn; gestational age less than 37 weeks; birth weight less than 1500g; using invasive mechanical pulmonary ventilation for at least 24 hours; be submitted to the first extubation attempt; presenting adequate gas exchange indicated by partial arterial oxygen pressure (PaO2) greater than 60 mmHg with FiO2 less than 0.4 and Support Pressure less than 16 cmH2O
Exclusion criteria
Exclusion criteria: Neurological or cardiac malformations; genetic syndromes; hemodynamic instability; signs of respiratory distress; inadequate tissue perfusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate if there is a difference in the prediction of extubation success between two different spontaneous breathing tests, 10 and 20 minutes. For this outcome, neonates who need reintubation and reinstitute ventilatory support within 48 hours after extubation will be considered as extubation failure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigate the effect of TRE on the diaphragm kinematics. The kinematics of the diaphragm will be assessed through the variables mobility and contraction speed through kinesiological ultrasound, before and immediately after the test. | — |
Countries
Brazil
Contacts
Public ContactAna Carolina D'Amorim
REAL HOSPITAL PORTUGUES DE BENEFICENCIA EM PERNAMBUCO
Outcome results
None listed