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Effect of Coconut Oil on Vaginal Hydration after Exposure to Cancer Treatment

Evaluation of the effect of coconut oil as a vaginal restructuring agent for patients undergoing chemotherapy and radiotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8hcb95v
Enrollment
Unknown
Registered
2024-07-24
Start date
2023-06-26
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radiotherapy

Interventions

This is a controlled, randomized, double-blind clinical trial type study. The research will take place in the Master's multidisciplinary laboratory and data collection will be carried out in the Gynec

Sponsors

Centro Universitário CESMAC
Lead Sponsor
Centro Universitário CESMAC
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Women with a confirmed diagnosis of cancer (all types) undergoing chemotherapy or radiotherapy; between 18-50 years old; with an active sexual life; who agree to the Informed Consent Form of this research

Exclusion criteria

Exclusion criteria: Women with secondary amenorrhea or menopause will be excluded from the study

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: It is expected to find an increase in the number of superficial epithelial cells in participants in the coconut oil intervention group, as well as a reduction in the signs and symptoms observed in menopausal genitourinary syndrome. The presence of cells was verified through colpocytology collection and signs and symptoms through recording in the medical record, based on comparative analysis between pre and post intervention.;Outcome found 1: In the experimental group with 10% coconut oil, before the intervention, the average percentage of the number of superficial cells was 11.129%, while 74.35% was intermediate and 14.53% was deep. After the treatment period, the average percentage of the number of superficial cells was 18.88%, while 72.35% were intermediate and 8.82% were deep. When comparing the mean percentage of cells before and after the intervention period, the test group was significant for superficial (p-value < 0.001) and deep cells (p-value < 0.001), indicating that there was a significant change in the mean percentage of cell in the groups before and after the intervention. Regarding the signs and symptoms of menopausal genitourinary syndrome, a significant reduction in burning (69.4%), burning (62.4%), dyspareunia (48.2%), dryness (73%), vaginal fissure was observed. (53%) and itching (48.2%) after intervention with coconut oil.

Secondary

MeasureTime frame
No secondary outcomes were expected

Countries

Brazil

Contacts

Public ContactWillams da Silva

Centro Universitário CESMAC

willams_alves@hotmail.com+55-81-999576266

Outcome results

None listed

Source: REBEC (via WHO ICTRP)