Chronic Periodontitis
Conditions
Interventions
Both the control and intervention groups were made up of 33 patients (split-mouth study). Two dental elements of each patient received placebo and the other two elements received the intervention crea
Sponsors
Universidade Estadual de Ponta Grossa
Universidade Estadual de Ponta Grossa
Eligibility
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Volunteers aged between 18 and 60 years; of both genders, with at least five teeth in each hemi-arch (including 16, 22, 36 and 32); who had probing sensitivity and features of chronic periodontitis with probing depth greater than or equal to 5mm
Exclusion criteria
Exclusion criteria: Use of prophylactic antibiotics before periodontal probing; psychiatric disorders or chronic pain; clotting disorders; anticoagulation therapy; pregnant or lactating women; congenital or idiopathic methemoglobinemia; treatment with methemoglobin inducing agents; allergic to anesthetics; use of steroidal or non-steroidal anti-inflammatory drugs in the three days prior to the start of the study and patients with acute periodontal pain, pulpitis, abscesses or other acute infections
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Topical application of EMLA 5% cream (lidocaine + prilocaine) is expected to reduce the prevalence of pain on probing from 77% to 40%. Thus, an alpha of 5% and a beta of 10% (90% power) were established, obtaining a minimum sample size of 33 volunteers for this clinical study. In addition to a reduction in pain on probing, it is expected to verify whether or not there is a difference in the degree of pain between groups (gender, age, among others) and between anterior and posterior dental elements;Outcome 1: The data obtained were submitted to two-factor ANOVA with repeated measures (anesthetic and type of tooth). The analysis showed no statistically significant difference between the application of anesthetic (35.4±23.7) and placebo (35.5±25.3), regardless of the type of tooth (p=0.982). There were also no differences between the types of teeth - molars and incisors - for pain reporting (p=0.303). Primary outcome measures showed that application of EMLA topical anesthetic gel is not effective in reducing probing pain in patients with chronic periodontal disease. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactDaniele de Oliveira
Universidade Estadual de Ponta Grossa
Outcome results
None listed