Postoperative Cognitive Complications
Conditions
Interventions
A double-blind, randomized, single-center clinical trial involving patients undergoing elective surgeries under general anesthesia lasting 60 to 120 minutes, aged 65 or older. The study will be conduc
Sponsors
Impar Serviços Hospitalares S/A
Centro de Ensino e Treinamento Hospital Regional do Gama
Eligibility
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients between 65 and 80 years of age of both genders; procedures under general anesthesia with an estimated duration of 60 to 180 minutes; physical status classified as American Society of Anesthesiologists (ASA) I a III
Exclusion criteria
Exclusion criteria: Patients with preoperative fever (> 38.0°C) or hypothermia (< 36.0°C); history of encephalopathy, autonomic neuropathy, thyroid dysfunction, risk of malignant hyperthermia, or neurological or cognitive diseases; patients with a Body Mass Index (BMI) over 35 kg/m²; preoperative tympanic body temperature outside the range of 36°C to 38°C; patients referred to the Intensive Care Unit (ICU) during the post-anesthetic recovery period; patients diagnosed with uncompensated thyroid disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A reduction in the duration of intraoperative hypothermia is expected to be observed in the pre-warming group compared to the control group | — |
Secondary
| Measure | Time frame |
|---|---|
| A reduction in the proportion of intraoperative hypothermia duration is expected in the pre-warming group;Evaluate the effects of anesthesia on cognitive function using CogniFit, considering domains such as memory, coordination, reasoning, short-term phonological memory, short-term visual memory, working memory, naming, response time, and processing speed | — |
Countries
Brazil
Contacts
Public ContactMarcella Souza
Centro de Ensino e Treinamento Hospital Regional do Gama
Outcome results
None listed