Rheumatoid arthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Volunteers with Rheumatoid Arthritis; both genders, aged 35 to 65 years; minimum period of 6 months from the last periodontal treatment; no use of antimicrobials in the period of 3 months prior to the study.
Exclusion criteria
Exclusion criteria: Volunteers diagnosed with other rheumatological diseases; diabetics; pregnant women; volunteers with disabling psychological or physical conditions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in the periodontal condition, verified by full-mputj manual periodontal probing, from the finding of reduction of probing depth by at least 2mm, of gain of clinical attachment by at least 2mm, of reduction of the plaque index of at least 10 % | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease in periodontal bacterial levels, verified by real-time PCR, based on the finding of a reduction in the counts of A. actinomycetemcomitans, P. gingivalis, T. forsythia, Dental T in at least 10%;Improvement in the disease activity of rheumatoid arthritis, verified through the DAS-28 index, from the finding of a reduction in DAS-28 values by at least 2 points | — |
Countries
Brazil
Contacts
Universidade Federal de Minas Gerais