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Validation of the GRACE Risk Score for Prediction of Hospital Death and Six Months After Discharge in a Patient with Acute Coronary Syndrome

Hospital Mortality and After Six Months of Admission According to the GRACE Score in Patients with Acute Myocardial Infarction with or without ST Segment Elevation and Patients with Unstable Angina - Global Registry of Acute Coronary Events (GRACE) Global Registry of Acute Coronary Events

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-8fvc8gx
Enrollment
Unknown
Registered
2020-12-07
Start date
2018-04-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction

Interventions

160 consecutive patients who were admitted to the Hospital de Clínicas de Passo Fundo diagnosed with acute coronary syndrome were evaluated. In addition, 6 months after the event, telephone contacts w

Sponsors

Faculdade IMED
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patient over 18 years old, have at least one of the following factors: Changes in the electrocardiogram (transient elevations of the ST segment greater than 1 mm, depressions of the ST segment greater than 1 mm, new inversions of T waves greater than 1 mm, pseudo-normalization of waves Previously inverted T waves, new Q waves (1/3 the height of the R wave or? 0.04 seconds), new R wave> S wave in V 1 (posterior MI), new left bundle branch block or changes must be made observed in two or more contiguous leads); Documentation of coronary artery disease (history of AMI, angina, congestive heart failure due to ischemia or resurrected sudden cardiac death; history of, or new positive stress test, with or without an image; previous or new cardiac catheterization, documentation of coronary artery disease or previous or new percutaneous coronary intervention or bypass surgery); Increased Cardiac Enzymes (CK (creatine kinase) -MB greater than twice the upper limit of the hospital reference range or if no CK-MB available, then total CPK (creatine phosphokinase) greater than twice the upper limit of the hospital reference range ; troponin I positive; or troponin T positive) and has accepted to participate in the research by signing the Informed Consent Form (ICF).

Exclusion criteria

Exclusion criteria: Patients who have lost contact within six months of the first interview; with clinical picture of inclusion but derived from a significant comorbidity, such as a motor vehicle accident, trauma, severe gastrointestinal bleeding, operation or procedure; and hospitalized patients who develop symptoms of ACS while hospitalized for any reason.

Design outcomes

Primary

MeasureTime frame
Evaluate the GRACE Score model using -C, defined by the area below the ROC curve. It is expected to validate the GRACE score in our study population. It was observed 160 patients who had an Acute Coronary Diet Syndrome observing the outcome of hospital mortality and 6 months after discharge.

Secondary

MeasureTime frame
To present an epidemiological profile of patients with acute coronary syndrome;Observe hospital mortality rate and 6 months after discharge

Countries

Brazil

Contacts

Public ContactVítor Neves

Faculdade IMED

vitor.vbn@gmail.com5554991737916

Outcome results

None listed

Source: REBEC (via WHO ICTRP)