The study is to assess the reduction of, PAIN , during anesthesia , conducted in human volunteers, previously screened healthy requiring dental treatment with anesthetic approach to sensory block the, PAIN.
Conditions
Interventions
We selected 10 individuals to participate in the study, all covered 2 times during development work, with the interval of 7 days in each procedure performed, which consisted of 10 patients participati
Drug
Procedure/surgery
D02.241.223.100.050.500.687
HP3.073.433.101
Sponsors
Centro Universitário Franciscano
Centro Universitário Franciscano
Eligibility
Inclusion criteria
Inclusion criteria: Patients over 18 years of age, healthy, with dental history allergic sensitivity to anesthetic free or their components. The maximum blood pressure to consider normotensive patients was 139/89 mmHg.
Exclusion criteria
Exclusion criteria: Patients with local and / or systemic change; smokers and pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the efficacy of topical anesthetic (benzocaine 20%) compared to placebo in reducing pain, heart rate and blood pressure at the needle puncture sites in anesthesia. Heart rate and blood pressure were assessed 10 minutes before needle puncture during the procedure, and 10 minutes after anesthetic infiltration using Omron® HEM 742 Automatic machine. The perception of pain was evaluated during needle puncture through the Visual Analogue Scale (VAS) in all experimental procedures.;When assessing the efficacy of topical anesthetic (benzocaine 20%) compared to placebo, we found that reduction of pain, quantified by the patients by a Visual Analog Scale, the needles to puncture the infraorbital region obtaining satisfactory results statistically (p = 0.04) with the use of topical anesthetic benzocaine 20%. Heart rate and blood pressure measured 10 minutes before the puncture needle at the time of the procedure, and 10 minutes after anesthetic infiltration using Omron® HEM 742 Automatic device. It resulted in no statistically significant difference. Data normality was tested by the Shapiro-Wilk test. Descriptive measurements were evaluated using mean and standard deviation. Differences between groups were evaluated using Student's t test. The level of significance was set at 5% | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain assessment in patients undergoing local anesthesia using topical anesthetic compared to placebo in local anesthesia in two regions of the oral cavity. Puncture needles to lock infraorbitary and posterior superior alveolar nerve.;The anterior maxillary region, innervated by infraorbitary has the largest presence of nerve endings, the prior application of 20% benzocaine topical anesthetic results in less pain in puncture needles for blocking the infraorbital nerve as compared to placebo, statistically confirmed (p = 0.04) using the Student's t test. | — |
Countries
Brazil
Contacts
Public ContactVinícius Cielo
Centro Universitário Franciscano
Outcome results
None listed