Endocrine, nutritional and metabolic diseases
Conditions
Interventions
Experimental group: 42 adults with obesity will receive 5gr (in sachets) of grape seed flour to consume during breakfast for 6 weeks
Control group: 42 adults with obesity will receive 5gr (in sachets)
Dietary supplement
G07.203.300.456
Sponsors
Luciana Pellegrini Pisani
Yasmin Alaby Martins Ferreira
Eligibility
Inclusion criteria
Inclusion criteria: Male and female adults; between 20 and 59 years old; residents from Baixada Santista; with obesity, BMI between 30 and 39.9 kg/m²
Exclusion criteria
Exclusion criteria: Regular or continuous use of anti-inflammatory or antibiotic medications in the last 3 months; chronic alcohol intake above 30grams per day; heart disease; liver disease; kidney disease; cancer; acute gastrointestinal problems, including diagnosed lactose intolerance; pregnancy or lactation; and menopause
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| To analyze the modulation of the intestinal microbiota by the profile of Lactobacillus, Bifidobacteria, Akkermansia and Clostridium Coccoides bacteria by PCR analysis before and after supplementation | — |
Primary
| Measure | Time frame |
|---|---|
| To evaluate the body composition improvement by bioimpedance after 6 weeks of consumption of grape seed flour. Data will be collected in the week before and after treatment;It is expected to find improvement in biochemical parameters such as blood glucose, insulin, lipid profile through biochemical analysis performed before and after supplementation | — |
Countries
Brazil
Contacts
Public ContactYasmin Ferreira
Universidade Federal de São Paulo
Outcome results
None listed