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Evaluation of chia seed in the improvement of oxidative stress in obese children and its relation with Vitamin E.

Evaluation of Oxidative Stress in Obese Children with Chia Seed Treatment (Salvia Hispanica) and its Implications for Vitamin E

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8dnw3g
Enrollment
Unknown
Registered
2018-03-14
Start date
2014-11-05
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

An intervention study will be performed with 30 obese children. During the study, the 30 patients selected will have the necessary samples to perform all the clinical analyzes collected on the day of
and group B, who will initially receive chia capsules, will receive placebo at this time. At the end of this new interval of 75 days, in the D165 will be collected the new samples necessary to carry o
Dietary supplement
SP6.051.227

Sponsors

Faculdade de Medicina do ABC - FMABC
Lead Sponsor
Faculdade de Medicina do ABC - FMABC
Collaborator

Eligibility

Age
5 Years to 10 Years

Inclusion criteria

Inclusion criteria: Children in the pre-pubertal age of 5 to 10 years, with a 95th percentile greater.

Exclusion criteria

Exclusion criteria: Serological comorbidities (HIV, Hepatitis B, Hepatitis C), neoplasms, inflammatory diseases and patients who have been hospitalized in the last six months.

Design outcomes

Primary

MeasureTime frame
Outcome 1: To verify the levels of vitamin E when associated to the use of chia seed and its effect on oxidative stress through biochemical and molecular biology exams before and after treatment with the seed. Only a greater variation of the serum vitamin value was observed in the group receiving chia supplementation than in the placebo group p 0.303.;Outcome 2: To verify if there was improvement in the inflammatory profile with the use of the chia seed, using methods of biochemical tests and molecular biology. It was possible to verify a statistically significant correlation between the delta of the markers and the presence of fiber in two inflammatory parameters: the TNF, with a p of 0.027 and the nf-Kappa ?, with a p of 0,059.

Secondary

MeasureTime frame
Secondary outcomes are not expected.

Countries

Brazil

Contacts

Public ContactCamila da Silva

Faculdade de Medicina do ABC - FMABC

mila1_saran@hotmail.com55(11)49935400

Outcome results

None listed

Source: REBEC (via WHO ICTRP)