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Evaluation of the effect of in-vein Lidocaine done on the surgery time on pain intensity and inflammatory substance concentration (IL-6) in patients submitted to Stomach Reduction Surgery by Video

Evaluation of the effect of perioperative intravenous Lidocaine on pain intensity and IL-6 concentration in patients submitted to Laparoscopic Gastroplasty - UNIFESP-EPM: Universidade Federal de Sao Paulo-Escola Paulista de Medicina

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8dghsc
Enrollment
Unknown
Registered
2019-07-10
Start date
2016-10-18
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesidade não especificada

Interventions

Patients will be submitted to bypass gastroplasty and divided into 2 groups. Experimental group: 50 patients will receive bolus dose of lidocaine (1.5mg/kg) in 10min, before anesthesia induction. Afte
Drug
Procedure/surgery
D02.065.199.092.500
C18.654.726.500
E02.570.500.062.750

Sponsors

Universidade Federal do Maranhão
Lead Sponsor
Universidade Federal do Maranhão
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients of both genders; obese; ASA 1 or 2; aged between 18 and 60 years old; submitted to laparoscopic gastroplasty

Exclusion criteria

Exclusion criteria: Diagnosis of cardiac, renal, hepatic, respiratory, psychiatric, oncologic diseases; allergy to lidocaine; who receive any analgesics 1 week before the surgery, or who receive blood derivates during the study

Design outcomes

Primary

MeasureTime frame
It wait the patients who receive intravenous lidocaine present lower pain intensity and lower use of morphine in 24h. Also, we wait low level of IL-6 in patients who receive lidocaine.—

Secondary

MeasureTime frame
It wait the patients who receive intravenous lidocaine present lower consumption of intraoperative sevoflurane and lower incidence of adverse effects.—

Countries

Brazil

Contacts

Public ContactCaio Marcio;CAIO MARCIO Oliveira;OLIVEIRA

Universidade Federal do Maranhão;UNIVERSIDADE FEDERAL DE SÃO PAULO

caiomboliveira@hotmail.com;caiomboliveira@hotmail.com+5598981810055;11-5576-4522

Outcome results

None listed

Source: REBEC (via WHO ICTRP)