sarcopenia
Conditions
Interventions
Group 1 - sample of 11 elderly patients with sarcopenia. Intervention: 24 sessions of systemic acupuncture. Procedures: bioimpedance, dynanometry, Up and Go test and blood sample collection were perfo
Procedure/surgery
H02.004
Sponsors
Universidade Católica de Brasília
Universidade Católica de Brasília
Eligibility
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: male and female seniors; sedentary; who were not under acunpuncture treatment during the survey period.
Exclusion criteria
Exclusion criteria: Individuals who were afraid of needles; with mobility problems that prevented them to attend the data collection and processing location; who presented difficulties of understanding the treatment and the applied tests
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome: improvement of muscle strength and function after acupuncture intervention. Method used to verify the expected desfection: bioimpedance, dinanometry and test up and go Presentation of the parameters: even if the values ??of the three groups were above the recommended levels, G1 presented the lowest values ??when compared to the other groups, with a significant difference in relation to G2 (p = 0.027) in the Pre and Post 1 moments. However, acupuncture intervention was not able to promote significant changes in body fat levels of G1 (p = 0.358). Values ??of the manual grip strength: G2 had lower values ??than the other groups, with a significant difference at the post-3 moment compared to G3 (p = 0.002). Although there was no statistical difference, G2 and G3 presented manual grip strength, while G1 presented more stable values ??in both limbs. In the evaluation of the functionality, G2 presented a slower TUG test time, but with no statistical significance. This group showed an upward trend in time, whereas G1 and 3 presented similar behavior, with a non-significant reduction of the test time (p = 0.86). From the obtained values ??the delta were calculated, with the pre-moment as covariant and there was no difference. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome: Acupuncture in the elderly with sarcopenia may alter the inflammatory markers IL-6, IL-10 and TNF-?. Method used to verify expected outcome: ELISA analysis of inflammatory markers IL-6, IL-10 and TNF-? through blood sample. Presentation of the parameters: Regarding IL-6, all groups presented similar behavior and difference Pos 2 moment in comparison to the pre-moment was annotated (p = 0.05). Even with a slight drop in values, they were still higher than expected (2.08 pg / ml). The values ??of IL-6 and TNF-? generally present direct correlation. In this study there was no relationship between the behavior of IL-6 and TNF-?. The groups showed no difference between them or between the evaluated moments. All groups presented lower than ideal values ??(4.12 pg / ml). IL-10 values ??showed a significant drop in G2 post-3 compared to baseline (p ? 0.001), indicating loss of anti-inflammatory cytokines that confer protection against the oxidative effects of aging. G1 and G3 showed a less significant decrease in IL-10 over the assessed period. All groups completed the study with values ??below the ideal (3.5 pg / ml). From the obtained values, the delta was calculated, with the pre-time as covariant and there was no significant difference. | — |
Countries
Brazil
Contacts
Public ContactGisele Mendes
Universidade Católica de Brasília
Outcome results
None listed