Adquired Immunodeficiency Syndrome (aids), lipodystrophy
Conditions
Interventions
The groups will be subdivided into individuals living with HIV (HIV +) and healthy sedentary (HIV-) participants, having a sample size estimated for 40 participants per group estimated by G.Power soft
and 3) shoulder development
4) Earth squatting
7) Straight abdominal. The adaptation to the training will be performed in two sets of ten to twelve repetitions (2 x 10-12 repetitions), in concentric and eccentric phases of 1: 1 second and loads ad
Other
G11.427.410.698.277
E02.760.169.063.500.387.875
Sponsors
Universidade Estadual de Maringá
Universidade Estadual de Maringá
Eligibility
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria for the study will be: to present a positive serology for the HIV virus and to be using ART for at least 6 months (closed to the HIV- group); be physically enabled (without any motor impairment) to perform the tests and trainings; have no severe disease; be between 18 and 60 years of age; present the cardiological medical certificate for the practice of physical exercises.
Exclusion criteria
Exclusion criteria: The exclusion criteria adopted for both groups (HIV + and HIV-) will be: present diarrhea, nausea, vomiting or poor oral intake of food; have had systemic infection within 30 days; pregnancy or have a presence of less than 85% of the training sessions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected Outcome 1: CD4 T and CD8 T lymphocyte count; one analysis will be by blood flow cytometry (12 hour fasting); An analysis metric will be the cell count (cells / mm3); The collection and analysis periods will be before (baseline), after 12 training sessions and 24 training sessions.;Expected Outcome 2: Analyze blood Adiponectin, Ghrelin, Leptin, Retinol Binding Protein, fibroblast growth factor 21, irisine, atrial natriuretic peptide and Resistin concentration; The analysis will use the multiplex ELISA by the enzyme immunoassay technique; The values will be analyzed by absorbance by the similarity of the points with the standard curve expressed in micrograms per milliliter. The collection and analysis periods will be before (baseline), after 12 training sessions and 24 training sessions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Expected Outcome 1: Analyze the participants' plasma biochemical parameters; Serum biochemical analyzes will be used to determine concentrations of glucose, cholesterol, triacylglycerol, low-density lipoproteins, high-density lipoproteins, very low-density lipoproteins, alanine aminotransferase and aspartate aminotransferase, creatine kinase and gamma glutamyl transferase using colorimetric kits. from Gold Analyzes. Data will be expressed in milligrams per deciliter; The collection and analysis periods will be before (baseline), after 12 training sessions and after 24 training sessions.;Secondary Expected Outcome 2: Analyze blood insulin, cortisol and dehydroepiandrosterone concentration; The analysis will be using the multiplex ELISA by the enzyme-linked immunosorbent assay technique; Samples will be analyzed for absorbance by similarity of points to the standard curve expressed in micrograms per milliliter. The collection and analysis periods will be before (baseline), after 12 training sessions and after 24 training sessions. | — |
Countries
Brazil
Contacts
Public ContactSidney Barnabé Peres
Universidade Estadual de Maringá
Outcome results
None listed