How home-based physical exercises can improve the health and quality of life of frail older adults in Belo Horizonte

Effects of Physical Exercise on the experience of older adults in Belo Horizonte at risk and in a situation of Frailty

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

REBEC

Registry ID

RBR-8d2kp7r

Enrollment

Registered

2026-02-09

Start date

2025-01-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Frailty

Interventions

This is a randomized, controlled, two-arm clinical trial developed within the context of the project “Effects of physical exercise on the experience of older adults at risk and in a situation of frail

Eligibility

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 60 years or older; the presence of established clinical frailty, as determined by a multidimensional assessment conducted by the research team.

Exclusion criteria

Exclusion criteria: Severe or decompensated clinical comorbidities; advanced cognitive impairment that would prevent them from understanding or performing the proposed intervention; immobility, defined as complete dependence on assistance for ambulation; or absence of a minimum level of family support necessary for participation in the study.

Design outcomes

Primary

Measure	Time frame
Expected Outcome 1: It is expected to observe an improvement in functional status among frail older adults undergoing a home-based Mat Pilates exercise program, performed twice a week for six months. Functional status will be assessed using the Barthel Index and the IVCF-20 scale, by comparing scores obtained before and after the intervention period. A positive outcome will be defined as an increase of at least 10% in the average scores compared to baseline values after the intervention.;Found outcome 1: No significant improvement in overall functionality was observed after the home-based Mat Pilates intervention. Analysis of the Clinical-Functional Vulnerability Index (IVCF-20) showed no significant intervention effect at 3 months (p = 0.388) or 6 months (p = 0.936). Likewise, no significant difference between groups was observed in the Barthel Index at the end of follow-up (p = 0.334). The predefined minimum increase of 10% in mean scores compared to baseline was not achieved.	—

Measure

Time frame

Expected Outcome 1: It is expected to observe an improvement in functional status among frail older adults undergoing a home-based Mat Pilates exercise program, performed twice a week for six months. Functional status will be assessed using the Barthel Index and the IVCF-20 scale, by comparing scores obtained before and after the intervention period. A positive outcome will be defined as an increase of at least 10% in the average scores compared to baseline values after the intervention.;Found outcome 1: No significant improvement in overall functionality was observed after the home-based Mat Pilates intervention. Analysis of the Clinical-Functional Vulnerability Index (IVCF-20) showed no significant intervention effect at 3 months (p = 0.388) or 6 months (p = 0.936). Likewise, no significant difference between groups was observed in the Barthel Index at the end of follow-up (p = 0.334). The predefined minimum increase of 10% in mean scores compared to baseline was not achieved.

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Secondary

Measure	Time frame
Expected Outcome 2: It is expected to observe an improvement in cognitive function among participants following the intervention. Cognition will be evaluated using the Mini-Mental State Examination (MMSE), verbal fluency test, and CERAD word list, by comparing pre- and post-intervention scores. A positive outcome will be defined as an average increase of at least 1 point on the MMSE or a statistically significant improvement in the other cognitive measures.;Expected Outcome 3: It is expected to observe a reduction in depressive symptoms among participants after six months of intervention. Depressive symptoms will be assessed according to DSM-V diagnostic criteria and clinical evaluation by comparing the frequency of symptoms before and after the intervention. A positive outcome will be defined as a reduction of at least 20% in the frequency of depressive symptoms or diagnoses. ;Expected Outcome 4: It is expected to observe an improvement in quality of life after the intervention. Quality of life will be assessed using the WHOQoL-OLD questionnaire, administered at baseline and at the end of the study. A positive outcome will be defined as an increase of at least 10% in the total WHOQoL-OLD score compared to baseline.;Expected Outcome 5: It is expected to observe an improvement in functional mobility among participants following the intervention. Mobility will be assessed using the Short Physical Performance Battery (SPPB), Timed Up and Go (TUG) test, gait speed, and the five-times sit-to-stand test, by comparing pre- and post-intervention results. A positive outcome will be defined as an increase of at least 10% in SPPB scores or a significant reduction in test times.;Found outcome 2: No significant differences in cognitive function were observed between groups after the intervention. Assessments using the Mini-Mental State Examination (MMSE) (p = 0.663), verbal fluency test (p = 0.390), and CERAD word list (p = 0.371) showed no significant improvement at the end o	—

Measure

Time frame

Expected Outcome 2: It is expected to observe an improvement in cognitive function among participants following the intervention. Cognition will be evaluated using the Mini-Mental State Examination (MMSE), verbal fluency test, and CERAD word list, by comparing pre- and post-intervention scores. A positive outcome will be defined as an average increase of at least 1 point on the MMSE or a statistically significant improvement in the other cognitive measures.;Expected Outcome 3: It is expected to observe a reduction in depressive symptoms among participants after six months of intervention. Depressive symptoms will be assessed according to DSM-V diagnostic criteria and clinical evaluation by comparing the frequency of symptoms before and after the intervention. A positive outcome will be defined as a reduction of at least 20% in the frequency of depressive symptoms or diagnoses. ;Expected Outcome 4: It is expected to observe an improvement in quality of life after the intervention. Quality of life will be assessed using the WHOQoL-OLD questionnaire, administered at baseline and at the end of the study. A positive outcome will be defined as an increase of at least 10% in the total WHOQoL-OLD score compared to baseline.;Expected Outcome 5: It is expected to observe an improvement in functional mobility among participants following the intervention. Mobility will be assessed using the Short Physical Performance Battery (SPPB), Timed Up and Go (TUG) test, gait speed, and the five-times sit-to-stand test, by comparing pre- and post-intervention results. A positive outcome will be defined as an increase of at least 10% in SPPB scores or a significant reduction in test times.;Found outcome 2: No significant differences in cognitive function were observed between groups after the intervention. Assessments using the Mini-Mental State Examination (MMSE) (p = 0.663), verbal fluency test (p = 0.390), and CERAD word list (p = 0.371) showed no significant improvement at the end o

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Countries

Brazil

Contacts

Public ContactAndré Chaves

Universidade Federal de Minas Gerais

andrechaves41@ufmg.br+5531999769260

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Mar 14, 2026