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Comparative study between lung expansion maneuvers in patients undergoing mechanical ventilation

Comparative study between alveolar recruitment maneuvers, chest compression and decompression maneuvers and breath stacking maneuvers in patients undergoing mechanical ventilation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8cykwc3
Enrollment
Unknown
Registered
2023-12-04
Start date
2018-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiration, Artificial

Interventions

This is a prospective, randomized study, which will be carried out in the Adult Intensive Care Unit of the Galileo Hospital and Maternity. Data collection will be carried out after approval of the pro
Group A (GA), where the patient will undergo alveolar recruitment
Group B (GB), where the patient will perform the chest compression and decompression maneuver/manual lung reexpansion maneuver and Group C (CG) where the patient will perform the breath stacking techn
and will then be subjected to the procedure of their respective drawn groups. In the
E02.779

Sponsors

Hospital e Maternidade Galileo
Lead Sponsor
Hospital e Maternidade Galileo
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with up to 72 hours of admission to the Intensive Care Unit (ICU) using mechanical ventilation (MV); patients of both sexes; aged 18 to 80 years; patients with hemodynamic stability, mean arterial pressure (MAP=60 mmHg), pulmonary gas exchange with partial pressure of oxygen greater than or equal to 60 mmHg (PaO2 = 60 mmHg), inspiratory fraction of oxygen greater than or equal to 60% (FiO2=60 %), positive expiratory pressure less than or equal to 10 cmH2O (PEEP=10 cmH2O), adequate oxygen saturation (SpO2=95%), acid-base balance; sedated or weaned patients; informed consent form signed by the responsible family member

Exclusion criteria

Exclusion criteria: Bronchopleural fistula; pulmonary thromboembolism; patients undergoing postoperative cardiac surgery; thrombocytopenia (<50,000/mm³); severe traumatic brain injury with intracranial hypertension (PIC=20mmHg); flail chest and undrained pneumothorax

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: With this study it will be possible to determine, in a scientific way, which of the techniques has a better effect on pulmonary ventilation or whether both are effective resources in reversing areas of hypoventilation and atelectasis, with consequent improvement in gas exchange without risk of injuries of the lung parenchyma;Found outcome 1: The two techniques studied (BSA and BSV) proved to be beneficial in ventilatory parameters. However, the superiority of BSV compared to BSA was observed, with better peak pressure (PIT) and Drive Pressure values ??in BSV with PIT -0.28±1.08 and Drive Pressure -0.12±0.97, while the BSA with PIT 0.34±1.45 and Drive Pressure 0.53±1.48. Low PIT and DP values ??demonstrate adequate lung distension – indicating that there is protection of the lung parenchyma, thus avoiding hyperinflation and possible injuries caused by barotrauma

Secondary

MeasureTime frame
Expected outcome 2: With this study it will be possible to determine, scientifically, whether all the techniques applied (breathstacking maneuver, alveolar recruitment maneuver and thoracic compression and decompression maneuver) are safe in maintaining patients' vital signs;Found outcome 2: When analyzing the vital signs of the present study, there were no significant changes in both techniques, demonstrating that they are safe in maintaining the vital signs of patients undergoing the techniques

Countries

Brazil

Contacts

Public ContactFabiana Della Via

Hospital e Maternidade Galileo

fisioterapia@hmg.com.br+55(19)2115-2000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)