Respiration, Artificial
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with up to 72 hours of admission to the Intensive Care Unit (ICU) using mechanical ventilation (MV); patients of both sexes; aged 18 to 80 years; patients with hemodynamic stability, mean arterial pressure (MAP=60 mmHg), pulmonary gas exchange with partial pressure of oxygen greater than or equal to 60 mmHg (PaO2 = 60 mmHg), inspiratory fraction of oxygen greater than or equal to 60% (FiO2=60 %), positive expiratory pressure less than or equal to 10 cmH2O (PEEP=10 cmH2O), adequate oxygen saturation (SpO2=95%), acid-base balance; sedated or weaned patients; informed consent form signed by the responsible family member
Exclusion criteria
Exclusion criteria: Bronchopleural fistula; pulmonary thromboembolism; patients undergoing postoperative cardiac surgery; thrombocytopenia (<50,000/mm³); severe traumatic brain injury with intracranial hypertension (PIC=20mmHg); flail chest and undrained pneumothorax
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: With this study it will be possible to determine, in a scientific way, which of the techniques has a better effect on pulmonary ventilation or whether both are effective resources in reversing areas of hypoventilation and atelectasis, with consequent improvement in gas exchange without risk of injuries of the lung parenchyma;Found outcome 1: The two techniques studied (BSA and BSV) proved to be beneficial in ventilatory parameters. However, the superiority of BSV compared to BSA was observed, with better peak pressure (PIT) and Drive Pressure values ??in BSV with PIT -0.28±1.08 and Drive Pressure -0.12±0.97, while the BSA with PIT 0.34±1.45 and Drive Pressure 0.53±1.48. Low PIT and DP values ??demonstrate adequate lung distension – indicating that there is protection of the lung parenchyma, thus avoiding hyperinflation and possible injuries caused by barotrauma | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: With this study it will be possible to determine, scientifically, whether all the techniques applied (breathstacking maneuver, alveolar recruitment maneuver and thoracic compression and decompression maneuver) are safe in maintaining patients' vital signs;Found outcome 2: When analyzing the vital signs of the present study, there were no significant changes in both techniques, demonstrating that they are safe in maintaining the vital signs of patients undergoing the techniques | — |
Countries
Brazil
Contacts
Hospital e Maternidade Galileo