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Effectiveness of dental care for prevention of nosocomial respiratory tract infections among intensive care patients.

Effectiveness of dental care for prevention of nosocomial respiratory tract infections among intensive care patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-89cp93
Enrollment
Unknown
Registered
2016-12-22
Start date
2011-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nosocomial respiratory tract infections, Bacterial pneumonia, not elsewhere classified

Interventions

Experimental group contained 147 patients that were submitted to dental care provided by a dental surgeon, as needed by the patient, four to five times a week until discharge from the intensive care u
Procedure/surgery
SP2.026
N06.850.780.200.450.150
E06.761.726.794
E06.721
E06.070
N02.278.354.422.298

Sponsors

Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Lead Sponsor
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Patients of both sexes, aged between 18 and 100 years old, admitted to the ICU of the study, if they had a expected time of hospitalization exceeding 48 hours.

Exclusion criteria

Exclusion criteria: Pregnancy, blood dyscrasia.

Design outcomes

Primary

MeasureTime frame
Expected outcome: Reduction in the incidence of lower respiratory tract infections during intensive care unit stay ;Observed outcome: there was a significant reduction in the incidence of lower respiratory tract infections during intensive care unit stay which was 8.7% in the experimental group and 18.1% in the control group (adjusted RR=0.44, CI95%=0.20-0.96, p=0.04).—

Secondary

MeasureTime frame
Expected outcome: Reduction on the duration of mechanical ventilation, lenght of stay in the intensive care unit, use of antimicrobial agents, and in-hospital mortality ;Observed outcome: Expected secondary outcomes were not observed, such as reduction on the duration of mechanical ventilation (11.3±9.0 days in the control group, 10.7±10.6 days in the experimental group, p=0.225), lenght of stay in the intensive care unit (10.9±8.7 days in the control group, 10.4±9.8 days in the experimental group, p=0.318), use of antimicrobial agents (8.7±8.0 days in the control group, 8.2±8.5 days in the experimental group, p=0,442), in-hospital mortality rates (31.5% in the control group versus 29.1% in the experimental group, adjusted RR=0.93, CI95%=0.52-1.65, p=0.796).—

Countries

Brazil

Contacts

Public ContactFernando Bellissimo-Rodrigues

Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo

fbellissimo@fmrp.usp.br5516 3602-2536

Outcome results

None listed

Source: REBEC (via WHO ICTRP)