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Fluoride levels in saliva after application of fluoride varnishes

Salivary fluoride bioavailability after the use of fluoride varnishes

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-8974jb6
Enrollment
Unknown
Registered
2023-02-03
Start date
2022-09-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluoride

Interventions

A randomized, crossover, double-blind clinical study (with regard to participants and researchers) was carried out. Sixteen adults aged between 20 and 32 years participated in this study, eight men an

Sponsors

Universidade Federal do Piauí
Lead Sponsor
Universidade Federal do Piauí
Collaborator

Eligibility

Age
20 Years to 32 Years

Inclusion criteria

Inclusion criteria: Favorable oral and systemic conditions; availability to participate in the research and comply with the determinations required by the experimental protocol; normal salivary flow; both genders; from 20 to 32 years old

Exclusion criteria

Exclusion criteria: use of medications that alter salivary flow; fluoride supplements; smokers; presence of active carious lesion; periodontal disease; fixed orthodontic appliance; allergy or sensitivity to the ingredients of the study varnishes

Design outcomes

Primary

MeasureTime frame
Determination of salivary fluoride concentration in saliva. It is expected to observe an increase in the salivary concentration of fluoride after the application of fluoride varnishes in the initial times after application with a subsequent decline.

Secondary

MeasureTime frame
Calculate the area under the curve of fluoride concentration in saliva over time. It is expected that the varnishes present a similar area under the curve value and that these values are greater when the fluoride dentifrice is associated with the varnish.

Countries

Brazil

Contacts

Public ContactGlauber Vale

Universidade Federal do Piauí

glauber@ufpi.edu.br+55(86)999129200

Outcome results

None listed

Source: REBEC (via WHO ICTRP)