Intensive Care Unit, Monitoring, Physiologic
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ICU patients; 18 years of age or over; both genders; under mechanical ventilation; with a degree of sedation equal to or greater than 4, measured by Ramsay scale; with central venous access (CVA); with prescription of motor physical therapy.
Exclusion criteria
Exclusion criteria: Patients with arterial access in the lower limbs; Grade 3 or 4 hypertonia, according to the Ashworth scale; Polytrauma or fractures not consolidated in the lower limbs; Patients in shock or infusion of high doses of vasoactive drugs; Patients with contraindication to bed elevation at 30 degrees or who did not tolerate the supine position.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of serum lactate, using the Lactate Gen.2 kit, in the COBAS INTEGRA, according to the technical standards of the Laboratory of Clinical Analysis (LEAC) of the São Francisco de Paula University Hospital. The hypothesis is that serum lactate will decrease 0.9 mg / dL after the early mobilization protocol.;The hypothesis was confirmed, with the pre-intervention lactate measurement of 15.41 (± 5.32) and post-14.44 (± 5.03), p value = 0.018. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic aspects, such as central venous saturation of O2, were determined based on the analysis of gasometry performed with Roche OMNI®S device, where no change was expected with the protocol. Heart rate and blood pressures were measured noninvasively by the multiparametric monitor, and a small increase, within the physiological limits, was expected for the greater venous return. As well as the respiratory rate obtained by the mechanical ventilator panel.;After the results, in relation to central saturation, the hypothesis was confirmed, with data pre - 71,84 (± 14,14) and post - 75,72 (± 9,19), there was no difference (p = 0.75) . Heart rate and mean blood pressure also confirmed hypotheses, with a significant increase in mean values of approximately 8 beats per minute (from 104.06 (± 25.29) to 112.81 (± 27.36), p = 0.007) and 10 mmHg (from 86.35 (± 11.28) to 95.83 (± 14.94), p <0.001) of the pre and post intervention measurement. The only outcome that did not confirm the hypothesis was the respiratory rate, which remained constant. | — |
Countries
Brazil
Contacts
Universidade Federal de Pelotas