diabetes mellitus
Conditions
Interventions
Prospective, randomized clinical study with two anesthetic intervention groups, each composed of 40 patients undergoing the proposed surgical procedure. In Group I, conventional general anesthesia wil
Sponsors
Universidade Federal de Goiás - UFG
Hospital Municipal de Aparecida de Goiânia Iris Rezende Machado
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: female or male patients aged 18 years or older and 65 years or younger, classified by the American Society of Anesthesiologists (ASA) as II, III, or IV; body mass index (BMI) equal to or greater than 30 kg/m²; patients scheduled for elective bariatric surgery; patients who agree to remain hospitalized for at least 24 hours; patients who voluntarily agree to participate in the study and sign the informed consent form
Exclusion criteria
Exclusion criteria: patients with known allergy or contraindication to any medication or anesthetic agent used in the study protocol; patients who, at any time during the study, refuse to remain in the study; patients who refuse to sign the informed consent form; patients with pharmacological dependence on opioid analgesics; patients undergoing therapeutic follow-up for any type of chronic pain; patients with a previous diagnosis of schizophrenia, bipolar disorder, or somatoform disorder; pregnant patients or women of childbearing potential with a positive quantitative human chorionic gonadotropin beta (hCG) test; patients with a history of stroke or motor endplate disease; patients with electrocardiographic findings of QT interval prolongation or second- or third-degree atrioventricular block; patients receiving chronic treatment with beta-blockers and with a preoperative heart rate below 50 bpm, or with heart failure with an ejection fraction below 40%; patients with hyperthyroidism or epilepsy; patients with chronic kidney disease with renal filtration rate classified as category G3b, G4, or G5
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a difference in postoperative pain intensity after bariatric surgery, assessed using the numerical pain scale in the immediate postoperative period and between 6 and 24 hours after the procedure; as associated primary outcomes, it is expected to find a difference in the occurrence of nausea and vomiting during the same period, assessed by the presence or absence of these events during postoperative follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find a reduction in pain at rest assessed by the numerical verbal scale at 6, 12, and 24 hours after surgery;It is expected to find a reduction in analgesic consumption during the first 24 hours after surgery;It is expected to find a reduction in opioid consumption during the first 24 hours after surgery;It is expected to find a reduction in the occurrence of ventilatory depression during the postoperative period;It is expected to find a reduction in the need for supplemental oxygen during the postoperative period;It is expected to find a reduction in the total length of stay in the post-anesthesia care unit | — |
Countries
BR
Contacts
Public ContactVergílio Carvalho
Universidade Federal de Goiás - UFG
Outcome results
None listed