Breast neoplasm
Conditions
Interventions
The study will be performed in a single institution, in female patients with breast cancer who will be submitted to adjuvant radiotherapy after conservative surgery in an attempt to prevent grade 2 ra
Radiation
Other
E02.186.775
Sponsors
Hospital de Amor de Barretos
Hospital de Amor de Barretos
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Female gender; Ductal Carcinoma in situ or Invasive; Lobular Carcinoma Invasive. Clinical stages 0; I; II or III (annex 2). Karnofsky performance scale (KPS) greater than or equal to 70% (annex 3). Age 18 years or older. Free and Informed Consent Form (annex 4) signed by the patient consenting to undergo the study. Treatment with adjuvant radiotherapy with a total dose of 6000cGy and without treatment to the lymphatic drainage of the supra clavicular fossa.
Exclusion criteria
Exclusion criteria: Male gender; non-conservative surgery; patient with collagen vascular disease; previous treatment with radiotherapy for the respective breast cancer; previous burn at the tumor site. Patient with mental disability. Patients undergoing chemotherapy (QT), except hormone therapy with tamoxifen, anastrozole or letrozole and monoclonal antibody with trastuzumab.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determine the effectiveness of the calendula cream or lotion in preventing radiodermatitis grade 2 and higher in patients with breast cancer, comparing them with patients using chamomile cream. | — |
Secondary
| Measure | Time frame |
|---|---|
| Observe the effectiveness of the treatments (Calendula Cream or Lotion versus Chamomile Cream), comparing the time until the occurrence of grade II radiodermatitis, adjusted with social-demographic and clinical characteristics.;Describe the toxic effects in each treatment. (eg allergic reactions). | — |
Countries
Brazil
Contacts
Public ContactRubem Fernando Lellis Andrade
Hospital de Amor de Barretos
Outcome results
None listed