Biotherapics
Conditions
Interventions
The study was based on a pilot case-control study involving 25 patients, with 16 allocated to the homeopathic biotherapeutics group and 9 to the placebo group. All participants underwent a complete pe
Sponsors
Universidade Veiga de Almeida
Universidade Veiga de Almeida
Eligibility
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: The selected individuals must present a Clinical Attachment Level (CAL) of moderate severity, equal to or greater than three or four millimeters, and severe cases equal to or greater than five millimeters, according to the American Association of Periodontology classification. The probing depth must be present in at least two proximal sites of two non-adjacent teeth. Both sexes
Exclusion criteria
Exclusion criteria: Individuals who have undergone any periodontal treatment in the past twelve months. Presence of aggressive periodontitis. Pregnancy and lactation. Prosthesis users. Medical conditions that may interfere, such as HIV, diabetes, or chronic lung disease. Individuals treated with inhaled corticosteroids, nonsteroidal anti-inflammatory drugs, or antibiotics used in the past six months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the clinical and microbiological efficacy of ultradiluted biotherapeutic therapy in the treatment of chronic periodontitis, measured by reduction in periodontal pocket depth , gain in clinical attachment level, reduction in visible plaque index and quantitative reduction in periodontopathogenic pathogens. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the safety and tolerability of ultradiluted biotherapeutic therapy, through: Adverse event monitoring: Recording and classifying the incidence and severity of adverse events related to the intervention during the follow-up period. Additional oral health parameters: Assessment of complementary indicators, such as the presence of inflammatory signs and subjective changes reported by patients | — |
Countries
Brazil
Contacts
Public ContactLeila Mourão
Universidade Veiga de Almeida
Outcome results
None listed