Severe acute malnutrition
Conditions
Interventions
This study has no groups.
Patients will undergo nutritional assessment within 72 hours of PICU admission and, if they remain hospitalized, they will be evaluated again on the seventh and fourteenth da
Other
Sponsors
Tiago Henrique de Souza
Tiago Henrique de Souza
Eligibility
Age
28 Days to 14 Years
Inclusion criteria
Inclusion criteria: Patients between 28 days and 14 years of age admitted to the pediatric intensive care unit.
Exclusion criteria
Exclusion criteria: Patients with a hospital stay of less than 48 hours; patients with neurodegenerative muscle diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measure will be the percentage of change in quadriceps femoris muscle thickness during the study period. Statistical analysis will be performed using MedCalc Statistical Software Version 14.8.1 (MedCalc Software bvba, Ostend, Belgium) and IBM SPSS Statistics for Windows Version 22.0 (IBM Corp, Armonk, NY). Kolmogorov-Smirnov test will be used to assess normality for continuous variables. Continuous variables will be expressed as a mean and standard deviation (SD) if data is normally distributed or as a median and interquartile range (IQR) if they not. Normally distributed variables will be compared using paired Student’s t-test. Non-normally distributed variables will be compared using Wilcoxon Signed-Rank Test. When appropriate, longitudinal analysis of the intake data, anthropometric and ultrasonographic measurements will be performed using analysis of variance (ANOVA) for repeated measurements. If the ANOVA revealed a significant interaction, post hoc analysis will be performed using the Bonferroni multiple comparisons test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will be changes in the anthropometric measurements of triceps skinfold thickness and mid-upper arm circumference. Statistical analysis will be performed using MedCalc Statistical Software Version 14.8.1 (MedCalc Software bvba, Ostend, Belgium) and IBM SPSS Statistics for Windows Version 22.0 (IBM Corp, Armonk, NY). Kolmogorov-Smirnov test will be used to assess normality for continuous variables. Continuous variables will be expressed as a mean and standard deviation (SD) if data is normally distributed or as a median and interquartile range (IQR) if they not. Normally distributed variables will be compared using paired Student’s t-test. Non-normally distributed variables will be compared using Wilcoxon Signed-Rank Test. When appropriate, longitudinal analysis of the intake data, anthropometric and ultrasonographic measurements will be performed using analysis of variance (ANOVA) for repeated measurements. If the ANOVA revealed a significant interaction, post hoc analysis will be performed using the Bonferroni multiple comparisons test. | — |
Countries
Brazil
Contacts
Public ContactTiago de Souza
Hospital das Clínicas da Universidade Estadual de Campinas
Outcome results
None listed