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The impact of physical exercise on inflammatory markers and functional capacity in people with chronic respiratory disease

The impact of pulmonary rehabilitation on inflammatory markers and functional capacity in patients with bronchiectasis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-85hvqq
Enrollment
Unknown
Registered
2018-12-27
Start date
2017-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiectasis

Interventions

Experimental Group: 70 individuals with bronchiectasis who will do physical exercises during 12 weeks, three times a week, 36 attendances in total with the appropriate medication. The protocol include
Other
G11.427.410.698.277
Q65.060

Sponsors

Hospital de Messejana Dr. Carlos Alberto Studart Gomes
Lead Sponsor
Hospital de Messejana Dr. Carlos Alberto Studart Gomes
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients of both gender with clinical diagnosis of bronchiectasis, with moderate or severe according with the FACED score: age between 18 and 80 years, clinically stable (without hospitalizations or infections in the last three months of the study beginning).

Exclusion criteria

Exclusion criteria: Patients who presented other respiratory chronic disease associated that needed treatment or urgent intervention; other disabling diseases, severe or with difficult control; patients who did not finished the study protocol and/or those who presented exacerbations during the period of their participation in the research.

Design outcomes

Primary

MeasureTime frame
Significant improvement of the inflammatory markers (fibrinogen, albumin, and PCR) after 12 weeks of the intervention protocol. ;Significant increase of the functional capacity from the increase of the walked distance in the six-minute walking test after 12 weeks of the intervention protocol.

Secondary

MeasureTime frame
Significant improvement in the quality of life using the quality of life questionnaires (SGRQ and LCQ) after 12 weeks of the intervention protocol. ;Significant decrease in the anxiety and depression score punctuation using the Beck Questionnaire of Anxiety and Depression after 12 weeks of the intervention protocol. ;Significant improvement of respiratory muscle strength using manovacuometry and the maximum strength of upper and lower limb using the one maximum repetition after 12 weeks of the intervention protocol. ;Significant improvement of fatigue and dyspnea using the fatigue severity scale and of the index of modified dyspnea (MMRC) after 12 weeks of the intervention protocol.

Countries

Brazil

Contacts

Public ContactAmanda Araújo

Hospital de Messejana Dr. Carlos Alberto Studart Gomes

amandasafisio@hotmail.com+55(85)997364603

Outcome results

None listed

Source: REBEC (via WHO ICTRP)