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Cellular functional response of the musculoskeletal system of hip replacement surgery patients

Proliferative and functional response of the musculoskeletal system of hip Arthroplasty patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-858ss8v
Enrollment
Unknown
Registered
2025-02-12
Start date
2024-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis, Hip

Interventions

The prospective study will sequentially include 40 patients with surgical indications for primary hip arthroplasty between November 2023 and February 2025, followed by the hip care area at the Nationa
G04.161.750

Sponsors

Instituto Nacional de Traumatologia e Ortopedia
Lead Sponsor
Instituto Nacional de Traumatologia e Ortopedia
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Over 18 years; hip arthroplasty eligible; both sexes

Exclusion criteria

Exclusion criteria: Neoplasm; positive viral diagnosis by serology or antigen (Hepatitis B, C and HIV); indication for revision hip arthroplasty surgeries

Design outcomes

Primary

MeasureTime frame
When comparing the underlying chronic degenerative disease of patients, it is expected to find a longer doubling time in cells obtained from patients with osteonecrosis compared to those with osteoarthritis in the evaluation of the proliferative response.—

Secondary

MeasureTime frame
Associate Tonnis radiological classification and osteoclasts differentiation profile—

Countries

Brazil

Contacts

Public ContactPatrícia dos Santos Costa

Instituto Nacional de Traumatologia e Ortopedia

patricia.costa@unirio.br+55(21)21345543

Outcome results

None listed

Source: REBEC (via WHO ICTRP)