Noninvasive ventilation, extubation, thoracic surgery
Conditions
Interventions
This is a cross-sectional study carried out in a Cardiothoracic Rehabilitation Unit (CTRU) of the Hospital Real Português of Pernambuco between May 2018 and July 2019 with individuals cardiovascular d
time 1 (T1-1 minutes from onset of NIV)
time 2 (T2 - last 5 minutes of NIV) and time 3 (T3 - one hour after disconnecting the NIV).
Procedure/surgery
E02.041.625.591
Sponsors
Universidade Federal de Pernambuco
Universidade Federal de Pernambuco
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Ages between 18 and 65 years; body mass index between 18.5 and 30 kgm2; undergo the Ultra Fast Track and Fast Track extubation techniques; without chronic obstructive pulmonary disease; pulmonary fibrosis; or chronic renal failure; or associated neuromuscular diseases; and those who have an American Society of Anesthesiologists perioperative risk score of less than 4.
Exclusion criteria
Exclusion criteria: Liver failure; congestive heart failure; dementia and Alsheimer's disease; left ventricular ejection fraction less than 40%; anticonvulsant; antidepressant; psychoactive drug in use and emergency reoperated patients; high surgical risk according to EuroSCORE II; presente cardiopulmonary bypass time great than 120 minutes; bleeding with thoracic drainage great than 100 mLh; renal failure with urine output less than 0.5 mLh in the first 6 hours; increased serum creatinine level less than 50% the baseline; prolonged inotropic and vasodilatory drugs support due to cardiac problems; extubation failure for hypercapnia; more than a failure in the autonomic test; mechanic ventilation assist time greater than 6 hours; hemodynamic instability; cardiogenic shock; severe hypotension with systolic blood pressure less than 90 mmHg; episode abdominal distress; nausea and vomiting; depressed level of consciousness; use of accessory muscle; respiratory rate great than 35 ipm; hypoxemia with PaO2 less than 50 mmHg with FiO2 of 50% or hypercapnia with PaCO2 great than 55 mmHg and with pH less than 7.30.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1 Alteration of ventilation and aeration lung, determined by electrical impedance tomography with a difference of at least 10% between the two groups. Data collected at baseline and at the end of the study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2 Reduction of 5% of arterial carbon dioxide pressure (paCO2), measured through arterial blood gas done at the beginning and at the end of the study.;Expected outcome 3 Increase of 5% of arterial oxygen pressure (PaO2), measured through arterial blood gas done at the beginning and at the end of the study.;Expected outcome 4 Increase of 5% in the oxygenation index (PaO2 / FiO2), measured through arterial blood gas done at the beginning and at the end of the study. | — |
Countries
Brazil
Contacts
Public ContactDaniella Brandão
Universidade Federal de Pernambuco
Outcome results
None listed