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The autonomic balance in asthmatic children

The autonomic nervous system in asthmatic children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-84r7t9
Enrollment
Unknown
Registered
2019-03-21
Start date
2015-12-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma

Interventions

ntervention (n=61) Adaptive training: All children underwent training in the diaphragmatic breathing technique, so that they learned and mastered the execution. The training took place in hospital env
Other
E02.190.525.186

Sponsors

Programa de Pós-graduação em Ciências da Saúde- PPGCS-FURG
Lead Sponsor
Hospital Universitário Dr. Miguel Riet Corrêa Jr. - HU-FURG
Collaborator

Eligibility

Age
7 Years to 18 Years

Inclusion criteria

Inclusion criteria: We included all children aged 7 and 18 years old and diagnosed with asthma, attended at the Pneumology outpatient clinic Pediatric Hospital of the University Hospital of the Federal University of Rio Grande (FURG), in the period between December 2015 and November 2016.

Exclusion criteria

Exclusion criteria: Patients with a diagnosis of bronchopulmonary dysplasia; cystic fibrosis; congenital cardiopulmonary diseases; immunodeficiency; chronic encephalopathy.

Design outcomes

Primary

MeasureTime frame
As primary endpoints we had the components Low Frequency (component of the low frequency range, 0.04 to 0.15 Hz, modulated by the sympathetic nervous system and by the parasympathetic and also related to the activity of the baroreceptors, with sympathetic dominance); and High Frequency (component of the high frequency range, 0.15 to 0.4 Hz, modulated by the parasympathetic nervous system, linked with respiration and changes in blood pressure). A Polar frequency meter, model RS800CX was used to collect Heart Rate Variability. ECG signal collection (1KHz sample rate) from the RR time series was acquired in the supine position with spontaneous breathing for 10 minutes. Subsequently the data were processed using KUBIOS HRV 2.0 Software (Kuopio, Finland).

Secondary

MeasureTime frame
As a secondary endpoint we had the ratio between the low frequency component and the high frequency component. The Low Frequency / High Frequency ratio reflects the interactions of the sympathetic and parasympathetic system in the autonomic modulation indicating the general autonomic balance. Values greater than 1 indicate the sympathetic domain, while values less than 1 indicate the parasympathetic domain and the value equal to 1 indicates absolute equilibrium. The ratio is obtained by the technique of Heart Rate Variability using appropriate software or by isolated calculation.

Countries

Brazil

Contacts

Public ContactOzeia Franco

Programa de Pós-graduação em Ciências da Saúde- PPGCS-FURG

professorozei@hotmail.com+55-053-991247609

Outcome results

None listed

Source: REBEC (via WHO ICTRP)