Muscle Weakness, diaphragm
Conditions
Interventions
This is a randomized crossover clinical trial with two arms and a blinded assessor. The study included 30 adult patients admitted to the intensive care unit for at least 48 hours, breathing spontaneou
Sponsors
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients (aged equal or higher than 18 years) admitted to the intensive care unit for at least 48 hours; breathing spontaneously; with a Glasgow Coma Scale score equal to or greater than 14
Exclusion criteria
Exclusion criteria: Neurological diseases; thoracic traumas; ascites; hemodynamic instability; pain at the moment of the assessment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find an increase in diaphragm excursion, assessed by ultrasound on the right hemidiaphragm, under the abdominal support condition. Measurements will be obtained during maximal inspiratory effort from residual volume to total lung capacity in the three breathing conditions (baseline, without abdominal support, and with abdominal support) | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to observe an increase in diaphragm muscle thickness and thickening fraction assessed by ultrasonography, as well as an increase in maximal inspiratory pressure, vital capacity, and tidal volume measured respectively by digital manovacuometer and spirometry under the breathing condition with abdominal support. | — |
Countries
Brazil
Contacts
Public ContactCaroline Mól
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Outcome results
None listed