Hypertension
Conditions
Interventions
40 patients will be recruited.All selected patients will be advised to consume the foods suggested by the DASH diet for approximately 6 months from the first consultation. For the adaptation of the di
Device
Behavioural
Other
Sponsors
Universidade Federal Fluminense
Universidade Federal Fluminense
Eligibility
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: Elderly female and male patients with body mass index (BMI) above 18.5 Kg / m² for both sexes, older than 60 years up to 85 and diagnosed with systemic arterial hypertension according to the study will be included in the study. the Brazilian Society of Cardiology criteria. The fit patients who were invited to participate in the research by reading and signing the Informed Consent Form (ICF). Patients will be followed for 6 months in monthly outpatient consultations, R24h were performed in all consultations in both groups. For GI patients, recipes adapted to the DASH diet model will be performed. Laboratory tests, body composition analysis and food frequency questionnaire will be performed at the beginning and end of the research. Patients will be followed up via phone contact, email or text messages weekly.
Exclusion criteria
Exclusion criteria: The study considered patients ineligible for prebiotics, probiotics, symbiotics supplementation in the last 3 months or receiving antibiotic therapy. Patients with glomerular filtration rate <60 ml / min, presence of pacemaker, presence of infectious or autoimmune disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in intestinal microbiota parameters is expected, investigated by counting Lactobacillus spp. patients, which will be evaluated by: Spontaneous evacuation stools will be requested at the first visit, collected by the patients and brought by them at the second visit, at the fifth visit the patients will be asked to bring the stool to the last visit for further analysis. They will be transported to the laboratory in a plastic bottle in refrigerated Styrofoam boxes for up to 6 hours. The method used for quantitative analysis of bacteria of the genus Lactobacillus spp in fecal samples will be the colony forming units (CFU) counting method before and after the follow-up period. For the preparation of the culture medium for isolation of Lactobacillus spp. In the fecal samples the MRS Agar, Scharlau ® base will be used. Weighing 66g from the base into the culture medium and diluting with 1 L of distilled water. The mixture will be boiled until completely dissolved and then stored in vials that will be autoclaved for sterilization at 121 ° C for 15 minutes (Montgomery et al., 2014). Weighing 1g of each patient's fecal samples for further dilution in 9 mL of 0.9% saline (10-1 dilution). Then, successive dilutions will be made to concentration 10-7 (Montgomery et al., 2014). For analysis of Lactobacillus spp. The technique will be per plate or deep sowing, in which 1 mL of each dilution is added to the still empty plate with subsequent addition of 15 mL of the prepared culture medium and then gently homogenized. All analyzes will be performed in duplicate to minimize technique and dilution errors. Then all plates will be incubated in a greenhouse at 35ºC. The average incubation time for is on average 72 hours. For colony counting, plates with growth between 30 and 300 colonies will be selected. Non-growing plates and uncountable plates, ie growth above 300 CFUs, will be excluded from the calculation. Counting results will be expressed in CFU / g stool.;It is also e | — |
Secondary
| Measure | Time frame |
|---|---|
| An improvement in anthropometric and body composition parameters is expected. Anthropometric measurements were performed at the first, third and last consultation with the individuals wearing light clothing and without shoes, in the standing position with their feet together. Weight, height and circumference values ??were obtained with minimum units of 0.1 kg, 0.5 cm and 0.1 cm, respectively. Circumferences were performed with flexible and inelastic tape without compressing the tissues (WHO, 2000). The weight was measured on a mechanical scale with a maximum capacity of 150 kg and 100 g division of Welmy brand. Height was measured with the Welmy stadiometer in inspiratory apnea. The head was oriented according to the Frankfurt plane (naturally straight head, looking forward), parallel to the ground. Height was measured with the cursor at an angle of 90 ° to the stadiometer scale (WHO, 2000). BMI was calculated with weight and height measurements according to the following formula BMI = weight (kg) / height² (m). The cutoff points were performed according to the criteria proposed by the Nutrition Screening Initiative that considers changes in body composition proper to aging, which are the cutoffs adopted for the elderly in Brazil according to recommendations of the Pan American Health Organization (PAHO, 2002). Waist circumference The perimeter of the (PC) was performed by palpation to identify the level of the lower costal margin and the iliac crest, in both places were marked a point with demographic pen, then transferred to the middle axillary line at the same height. Then with the tape measure the distance between the two markings was measured and at the midpoint the tape was passed to perform the reading (Lohman et al., 1988). The cutoff points adopted for WC were those recommended by WHO. Calf girth The measurement was performed with the individual in the upright position, with the feet 20 cm apart, and the tape was passed in the area with the larges | — |
Countries
Brazil
Contacts
Public ContactTaianah Barroso
Centro de Atenção à Saúde do Idoso e Cuidador
Outcome results
None listed