Parkinsons disease
Conditions
Interventions
The resistance training with instability protocol will have an intervening period of 12 weeks, 3 months, and trainings will be performed three time per week
every four weeks training loads will be adjusted progressively during the 12-week intervention
the intensity will be determined by the zone of maximum repetition, that is, the load used in each exercise must be maximal in order to set the number of repetitions
will be conducted at 7 exercises two for the upper limb and five for lower limb in both types of training
accessories will be added to cause instability, such as balance pad, balance disc, dyna disk, Bos, and ball these accessories will serve to cause instability where strength exercises are conducted con
will be part of the study 2 groups: control group 1 - 15 elderly individuals with Parkinson's disease in the stages 3 and 4 and having medical clearance to exercise, however, these patients will not p
control group 2 - resistance training with instability - 17 elderly individuals with Parkinson's disease in the stages 3 and 4 and having medical clearance to exercise
Dietary supplement
Other
I02.233.543
Sponsors
Escola de Educação Física e Esporte da Universidade de São Paulo
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Eligibility
Age
49 Years to 85 Years
Inclusion criteria
Inclusion criteria: All patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional; All patients must present the clinical diagnosis of Parkinson's disease obtained by a neurologist; to present freezing of the gait; to present between 49 and 85 years of age; to present Parkinson's disease between stages 3 and 4 and do not perform regular exercise weights six months before starting the training intervention.
Exclusion criteria
Exclusion criteria: Patients who present symptoms of dementia; depression; joint problems; cardiovascular diseases (except hypertension) and claustrophobia will be excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease in 5 points in the severity of the gait blockage verified through the score of the New Freezing of Gait Questionaire in the measurements before and after 3 months of intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease in 4 points in the severity of motor symptoms verified by the score of the Unified Scale of Parkinson's Disease Scale part III in the measurements before and after 3 months of intervention;Decrease in 20% in the frequency and duration of motor blockade verified by accelerometry of the lower limb in the measurements before and after 3 months of intervention;Reduction in 10% in the frequency and duration of motor block in double task verified by accelerometry of the lower limb in the measurements before and after 3 months of intervention;Improvement in 18% in the parameters of gait (with and without dual task), cadence, velocity, distance, step length and gait variability, verified by accelerometry of the lower limb in the measurements before and after 3 months of intervention;Improvement in 11% and 8% in the amplitude and time of the anticipatory postural adjustment, respectively, during the initiation task of the step evaluated on the force platform in the measurements before and after 3 months of intervention;Improvement in 15% in the static and dynamic balance verified by the Mini Test of Balance Evaluation System in the measurements before and after 3 months of intervention;Improvement in 18% in the stability of the automatic postural response concomitantly with electromyography verified in the mobile force platform in the measurements before and after 3 months of intervention;Improvement of 12% in attention and processing speed verified by the Digit Symbol Substitution Test score in the measurements before and after 3 months of intervention;Improvement in 11% in executive function verified through the Trail Making Test Section A and B in the measurements before and after 3 months of intervention;Improvement of 6 points in the cognitive function verified through the Montreal Cognitive Evaluation score in the measurements before and after 3 months of intervention;Improvement of 19% in the processing speed, attention and inhibitory control verified by the | — |
Countries
Brazil
Contacts
Public ContactCarlos Ugrinowitsch
Escola de Educação Física e Esporte da Universidade de São Paulo
Outcome results
None listed