Muscle weakness
Conditions
Interventions
Single group: 100 patients with severe COVID will undergo the following tests and scales on the day of admission to the ward (after ICU discharge): ICU mobility scale
Medical Research Council scale
hand grip strength
1-minute sit/stand test, and respiratory muscle strength. On the seventh day of admission to the ward, these tests and scales will be repeated and will be added: the 4-minute step test, assessment of
E01.370.600.425
Sponsors
Universidade Federal de São Paulo
Instituto do Coração -InCor - HCFMUSP
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients diagnosed with COVID-19, Need for invasive or non-invasive ventilatory support for more than 24 hours, Planning for ICU discharge.
Exclusion criteria
Exclusion criteria: Neurological or cognitive damage that compromises the execution of the tests.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in functional capacity (time frame 7 days). Assessed with Scored Physical Perfomance Battery and hand grip test.;Change in muscle strength (time frame 7 days). Assessed with Medical Research Council score.;Correlation among sedation, neuromuscular blocking and functional capacity. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in exercise capacity (time frame 7 days). Assessed with six-minute walk test and step test.;Changes in health-related quality of life (time frame 12 months) assessed with WHOODAS.;Change in respiratory strength (time frame 7 days). | — |
Countries
Brazil
Contacts
Public ContactMarcia Volpe
Universidade Federal de São Paulo
Outcome results
None listed