Fibromyalgia
Conditions
Interventions
Experimental group: 20 women, aged 35-70 years, with confirmed diagnosis of fibromyalgia, volunteers should be at the site at 7 am and 30 minutes in the morning, fasted for at least 8 hours and should
Device
Other
Sponsors
Universidade Federal dos Vales do Jequitinhonha e Mucuri
Fundação De Amparo a Pesquisa de Minas Gerais
Eligibility
Sex/Gender
Female
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: Women aged 35 to 70 years; with confirmed diagnosis of fibromyalgia between 1 and 3 years; presence of sensitivity in at least 11 of the 18 specific pain points according to the American College of Rheumatology criteria.
Exclusion criteria
Exclusion criteria: Volunteers who present; any concomitant illness that may be exacerbated by physical activity; pregnancy; orthopedic limitations; inflammatory diseases; degenerative diseases; articular; respiratory or cardiovascular diseases; who are being followed up with a psychiatrist; who perform physical activity for the same 2 times a week; (acute hernia, thrombosis, diabetes, epilepsy, metabolic or neuromuscular diseases, orthopedic injuries and prosthetics); use immunosuppressive medication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The VCI is expected to promote changes in redox status that may explain possible mechanisms for understanding the pathophysiology of FM. For determination of redox status parameters, whole blood will be collected aseptically using heparin as anticoagulant. The plasma will be separated by centrifugation and stored at -80øC until the experiments are performed. To evaluate the redox balance, the concentration of thiobarbituric acid (TBARS), total antioxidant capacity (FRAP), antioxidant enzyme superoxide dismutase (SOD) and catalase (CAT) activity of the samples collected before and immediately after the acute training on the platform vibration. ;Determination of the concentration of thiobarbituric acid: reaction of thiobarbituric acid with Malondeiodo, the main product of lipid peroxidation, will be used to determine thiobarbituric acid concentration, according to the method described by Ohkawa et al. (1979).;Determination of FRAP concentration: The total antioxidant capacity assay will be performed according to (BENZIE, et al., 1996). ;Determination of superoxide dismutase activity: The assay to determine SOD activity will be performed according to Srivastava (2007). ;Determination of catalase activity: the assay will be performed according to the method of Nelson and Kiesov (1972). | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain intensity reduction, which will be assessed by applying the visual analogue pain scale (VAS), which varies from 0 to 10 where 0 consists of no pain and 10 the maximum of persistent pain at the moment. ;Perception subjective exertion, through the Borg scale ranging from 6 to 20, where 6 consists effortlessly and 20 the maximum effort that persists at the time, before and immediately after the acute stimulus of whole body vibration in both groups. | — |
Countries
Brazil
Contacts
Public ContactAna Cristina Lacerda
Universidade Federal dos Vales do Jequitinhonha e Mucuri
Outcome results
None listed