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Comparison of brain connections post open-surgery or carotid angioplasty through functional Magnetic Resonance Imaging

Brain connections analysis post Endarterectomy versus Stent carotid Angioplasty by functional Magnetic Resonance in rest state

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-83j396
Enrollment
Unknown
Registered
2018-05-15
Start date
2013-10-23
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Occlusion and stenosis of carotid artery

Interventions

Functional magnetic resonance imaging in resting state (rs-fMRI) was obtained in pre and post-operative period of 33 patients with carotid stenosis. Eighteen patients for group 1 (CEA) and 15 patient
Device
Procedure/surgery
E04.100.814.456.250

Sponsors

Instituto de Neurologia e Neurocirurgia de Passo Fundo
Lead Sponsor
União Brasileira de Educação e Assistencia
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients 18 years old or older; with carotid stenosis above 60% asymptomatic; or patients who had a transient ischemic attack (TIA) with carotid stenosis above 50%; or ulcerated plaque; who agree to participate in the study

Exclusion criteria

Exclusion criteria: Patients with severe neurological disease such as parkinsonism, dementia, epilepsy, defined cerebrovascular disease, encephalopathy, severe depression; Patients who use drugs that directly affect the central nervous system, which prevent individualized natural responses to the tests

Design outcomes

Primary

MeasureTime frame
Increase in carotid revascularization compared by resting state functional Magnetic Resonance Imaging between endarterectomy or carotid artery stenting

Secondary

MeasureTime frame
Cognitive deficits caused by carotid revascularization compared between endarterectomy or carotid artery stenting;Improvement in cognitive outcomes due to carotid revascularization compared between carotid artery endarterectomy or stent procedures;Relationship between transcranial doppler microemboli, assessed by Doppler ultrasound, during carotid revascularization procedures and cognition, assessed through neuropsychological evaluations

Countries

Brazil

Contacts

Public ContactMarcelo Crusius

Instituto de Neurologia e Neurocirurgia de Passo Fundo

mucrusius@icloud.com+55-054-33117011

Outcome results

None listed

Source: REBEC (via WHO ICTRP)