Kidney Failure, Chronic
Conditions
Interventions
This study will include approximately 100 individuals diagnosed with Chronic Kidney Disease (CKD), either under conservative treatment or on hemodialysis, recruited from clinics and outpatient service
C12.777.419.780
E02.335.686.400
G02.403.810
G11.427.410
A13.869.161
D23.050.301
I01.880.735.950
Sponsors
Universidade Católica de Brasília
Universidade Católica de Brasília
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Volunteers diagnosed with chronic kidney disease; age minimum eighteen and age maximum sixty five years; physically inactive.
Exclusion criteria
Exclusion criteria: Smoker volunteers; diagnoses of cardic; gastrointestinal; hepatic; pulmonary; neurological; psychiatric; hematological or metabolic autoimmune diseases; diagnosis of sleep disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal Function of Patients in Conservative Stage by Estimated Glomerular Filtration Rate (eGFR): Baseline and every two months until the end of the protocol | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life as secondary measures of SF-36 : Baseline and every two months until the end of the protocol;Improvement in Inflammatory Biomarkers, Renal Health, Cardiovascular Function, and Metabolism: Interleukin 6, Interleukin 10, BDNF, Tumor Necrosis Factor, Nitric Oxide, Lactate, KIM-1, NGAL, Indoxyl Sulfate, p-Cresyl Sulfate, TMAO, TNF-a, IL-6, ADMA, and Leptin: Baseline and every two months until the end of the protocol ;Improvement in Microbiota Diversity and Composition: Microbial DNA Extraction from Feces. Baseline and at the end of the protocol;Improvement in Serum Lipid Levels Assessed by Measurements of Total Cholesterol (TC), LDL-c, HDL-c, and Triglycerides: Baseline, in real-time for 14 days, and two months after the protocol;Blood Glucose Levels Continuously Monitored via the Libre Sensor: Baseline, in real-time for 14 days, and two months after the protocol;Improvement in Physical Fitness Assessed by the Cardiopulmonary Exercise Test (CPET): Baseline and every two months until the end of the protocol ;Isometric Muscle Strength Assessed by Handgrip Strength Test: Baseline and every two months until the end of the protocol ;Score >9 Assessed by the Becker Depression Scale: Baseline and every two months until the end of the protocol | — |
Countries
Brazil
Contacts
Public ContactJessica Barbosa
Universidade Católica de Brasília
Outcome results
None listed