Sarcopenia
Conditions
Interventions
1008 patients with renal failure undergoing hemodialysis at several dialysis centers in Brazil will be evaluated for sarcopenia (low physical function and low muscle mass) and prospectively followed u
V03.175.500
Sponsors
Centro Universitário ICESP
Universidade de Brasília
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: equal or older than 18 years; hemodialysis treatment for at least three months.
Exclusion criteria
Exclusion criteria: Inability or refusal to sign/provide the informed consent form; Any impairment that compromises participation in the study, such as cognitive impairment, locomotor and/or neurological disorders; Change of renal replacement therapy or clinical center (non-partner) during the data collection phase, in a previously planned way, or during the follow-up; Medical contraindication for carrying out the battery of physical tests; Permanent pacemaker (contraindication to bioimpedance measurement); Uncontrolled heart disease, cardiovascular surgery, or recent hospitalization (one month before baseline).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We expect to find out the determinants of the transitions between sarcopenia stages (pre-sarcopenia, sarcopenia, and confirmed sarcopenia), assessed according to the revised European Working Group on Sarcopenia in Older People consensus (muscle strength, muscle mass, and physical performance). | — |
Secondary
| Measure | Time frame |
|---|---|
| We expect to verify an association of sarcopenia traits, assessed by muscle strength, muscle mass, and physical performance, with clinical outcomes (i.e., falls, hospitalization, and mortality) assessed by medical records. | — |
Countries
Brazil
Contacts
Public ContactHeitor Ribeiro
Centro Universitário ICESP
Outcome results
None listed