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Qualitative somatosensory clinical evaluation of recipient and donor sites of subepithelial connective tissue Grafts

Somatosensory profile in recipient areas of connective tissue Graft and donor palate: retrospective qualitative sensory evaluation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7zz3b6p
Enrollment
Unknown
Registered
2024-01-12
Start date
2019-09-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Recession

Interventions

The sample consisted of 82 systemically healthy individuals aged 18 to 70 years, following the inclusion criteria: normal and healthy palatal area, multiple gingival recessions (RT1) with at least one

Sponsors

Universidade de São Paulo
Lead Sponsor
Universidade de São Paulo
Collaborator
Faculdade de Odontologia de Bauru da Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients of both genders; age between 18 - 70 years; normal and healthy palatal area; multiple gingival recessions (RT1) with at least one gingival recession = 2 mm, including canines and premolars; systemically healthy patients with no contraindication to periodontal surgical procedures

Exclusion criteria

Exclusion criteria: Patients with prostheses with palatal coverage; palatal areas previously submitted to graft removal; teeth Mobility; smokers; pregnant and lactating women; history of periodontal disease or recurrent abscess formation; previously root coverage surgical procedures; use of medications (anticonvulsants, antihypertensives, contraceptives, or immunosuppressants) or drugs that influence wound healing; and a low level of oral hygiene (plaque index and bleeding index >20%)

Design outcomes

Primary

MeasureTime frame
Desfecho esperado 1: The objective of this study is to qualitatively evaluate the somatosensory sensitivity of areas that received subepithelial connective tissue grafts, of areas palatal donors of these grafts and assess whether there is a correlation with lifestyle. The evaluation will be verified using the qualitative sensory evaluations test, the Douleur Neuropathique 4 questionnaire and the Two-point Acuity Test. Qualitative sensory evaluations (QualST) were conducted in grafted areas compared to adjacent non-grafted areas and in donor areas compared to adjacent areas without intervention at three time points (baseline and after 3 and 6 months). Assessments of adjacent non-intervened areas are essential for intrapersonal comparison of somatosensory characteristics, validating the methodology employed. The protocol was performed using a flexible cotton swab, bristles of a toothbrush, a metal spatula (previously immersed in a container of ice-cold water), and a wooden stick. These instruments assessed dynamic tactile, cold thermal, and painful sensations. Participants were asked to report hypo (hyposensitive: -1), hyper (hypersensitive: +1), or normosensitivity (normosensitive: 0) when comparing the surgical areas (donor and recipient sites) to adjacent non-intervened areas. The Douleur Neuropathique 4 questionnaire was administered at 3 and 6 months postoperatively to assess items related to painful or non-painful sensations, using descriptive terms such as burning, painful cold sensation, electric shock, prickling, and tingling. For non-painful sensations, descriptors such as burning, electric shock, tingling, numbness, and itching were also employed. Furthermore, in the case of a positive response to painful or non-painful sensations, the frequency and duration were reported, as well as whether induced by brushing or chewing. The questionnaire also included a visual analog scale regarding the impact of these painful or non-painful sensations on the ability to

Secondary

MeasureTime frame
No secondary outcomes are expected.

Countries

Brazil

Contacts

Public ContactEsther Nascimento

Universidade de São Paulo

estherbelotti@usp.br+55(14)3235-8000

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 6, 2026