Brain Injuries
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: diagnosis of acute neurological injury; aged between 18 and 65 years; use of invasive mechanical ventilation (IMV); with more than 24 hours of acute brain event or neurosurgery; admitted to the ICU
Exclusion criteria
Exclusion criteria: diagnosis of Deep Venous Thrombosis (DVT); diagnosis of brain death (BD); no motor response to the stimulus of the electrostimulator; present criteria for interrupting or not performing the cycle ergometer more than 2 consecutive times or more than 5 times during the ICU stay; express request from a patient or family member to withdraw from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Muscle morphology, assessed through the use of ultrasound by analyzing the thickness, cross-sectional area, echo intensity, fascicle angle, muscle fascicle length, up to 24 hours after admission, every 5 days and on the day of discharge;Expected outcome 2: Muscle strength, assessed using the peak torque evoked by neuromuscular electrostimulation, 24 hours after sedation was off and on the day of discharge from the ICU;Expected outcome 3: Mobility, assessed using the ICU mobility scale after sedation is switched off and daily until discharge from the ICU | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Functionality, assessed using WHODAS 2.0 two months after discharge from the ICU | — |
Countries
Brazil
Contacts
Universidade Federal do Vale do São Francisco