Healthy Volunteers
Conditions
Interventions
The study is a crossover, randomized and controlled clinical trial, and will be composed of forty-nine individuals classified as normal-weight and overweight. Each participant will experience each con
G11.427.695.575
Sponsors
Universidade Federal de São Carlos (UFSCar)
Universidade Federal de São Carlos (UFSCar)
Eligibility
Age
23 Years to 45 Years
Inclusion criteria
Inclusion criteria: Be between 23 and 45 years of age; work for a period equal to or greater than 4 hours in a seated position and use the computer as their main work tool; not report suffering of chronic health problems; being a non-smoker for more than 1 year; for women, being in the follicular phase, in the period between the seventh and tenth day of the menstrual cycle, i.e., between the end of menstruation and mid-cycle; agreeing to participate in the study; and, not having symptoms of coronavirus disease 2019 (COVID-19).
Exclusion criteria
Exclusion criteria: Having a physical condition that prevents them from performing postural changes from sitting to standing or standing for more than 20 minutes; having signs and symptoms of pregnancy or being in gestational period; report having cardiovascular diseases [heart failure, coronary artery disease, arterial hypertension, changes in heart rhythm (atrial fibrillation, ventricular arrhythmia, ventricular tachycardia), valvular heart disease, acute myocardial infarction]; having the following conditions: type 1 and 2 diabetes, cardiac pacemaker, personal or family history of venous thrombosis or pulmonary embolism, presence of stroke sequelae; being an alcoholic, user of tobacco, nicotine products and illicit drugs; regularly use immunosuppressive drugs, corticosteroids, vasodilators, anxiolytics, beta-blockers and insulin; women with regular use of contraceptives or hormone replacement; and, menopausal women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We expect to verify that the indices of cardiovascular autonomic modulation in the experimental condition of alternating between sitting and standing in the sit-stand table will show higher activation of the sympathetic branch of the cardiac and vascular autonomic nervous system (ANS) compared to the sitting condition. Furthermore, we expect Baroreflex Sensitivity (BRS) to be increased in the sitting condition since this variable is influenced by sympathetic modulation of the ANS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected. | — |
Countries
Brazil
Contacts
Public ContactLuiz Augusto Brusaca
Universidade Federal de São Carlos (UFSCar)
Outcome results
None listed