Respiratory failure
Conditions
Interventions
This is a randomized clinical trial with two arms, not blinded for outcome measurement. The study population will consist of men and women admitted to an intensive care unit, and who have undergone in
Sponsors
Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUI
Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUI
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Over 18 years of age; both genders; intubated patients; more than 24 hours on an invasive ventilatory system; tolerate spontaneous breathing test with Tayre connected to oxygen therapy support; arterial blood gases in stable state
Exclusion criteria
Exclusion criteria: Pregnancy; existing spinal cord injury; neurodegenerative diseases; need for emergency intubation; cardiac or respiratory arrest; facial and cranial trauma or surgery; tracheostomy; recent oral gastric or esophageal surgery; upper gastrointestinal bleeding; excessive amount of respiratory secretions; uncooperative patient; presence of hearing and vision deficits; patient who does not tolerate the spontaneous breathing test and previous medical decision to limit therapeutic effort
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assess comfort using a visual analog scale before, during, and after the use of non-invasive ventilation in both protocols | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of adverse events associated with the use of NIV, assessed using the questionnaire method previously documented in the literature;Evaluation of the effectiveness of non-invasive ventilation, considering the extubation success rate and the reintubation rate in the first 48 hours;Total length of stay in the intensive care unit in days;Blood gas data obtained through blood gas analysis evaluating hydrogen ion potential, partial pressure of oxygen, partial pressure of carbon dioxide, and sodium bicarbonate before extubation, 1 hour after the initiation of non-invasive ventilation, and again after the removal of non-invasive ventilation, at the end of both protocols;Hemodynamic data assessing peripheral oxygen saturation, systolic blood pressure, diastolic blood pressure, heart rate, and respiratory rate before extubation, 1 hour after the start of non-invasive ventilation, and again after the removal of non-invasive ventilation, at the end of both protocols | — |
Countries
BR
Contacts
Public ContactEdina Steffens
Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUI
Outcome results
None listed