Hereditary factor VIII deficiency
Conditions
Interventions
A cross-sectional observational study in which 24 people with Haemophilia and 24 without hemophilia will be selected, who will be submitted to pain assessment by pressure algometry and joint hematolog
Device
Other
E01.370.600.550.324
Sponsors
Universidade Federal do Paraná
Universidade Federal do Paraná
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Diagnosis of moderate or severe A or B haemophilia;individuals aged between 18 and 60 years of age;subjects in follow-up with the multidisciplinary team at the Haemophilia Orthopedics outpatient clinic at CHC-UFPR; individuals who have had the infusion of clotting factor VIII or IX immediately prior to the evaluation;be able to understand verbal command and carry out the proposed evaluations;being prophylaxis with coagulation factor VIII or IX between 2-3 times per week as prescribed by the hematologist;individuals who agreed to participate in the study by signing the free and informed consent form.
Exclusion criteria
Exclusion criteria: Diagnosis of others coagulopathies; not within the age range specified above; patients who have undergone an orthopedic surgical procedure for arthroplasty; who do not perform prophylaxis with factor VIII or IX between 2-3 times a week; that they did not infuse the factor immediately before the evaluation; individuals unable to realize and understand the proposed evaluations
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presentation of the expected outcomeIncreased pain threshold measured by pressure algometry in subjects with Hemophilia compared to individuals without Hemophilia. The evaluation will be carried out only once. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactAna Carolina de Macedo
Universidade Federal do Paraná
Outcome results
None listed