Renal failure, sleep apnea, psychological stress, anxiety, depression and, quality of life.
Conditions
Interventions
Will be invited 57 patients to participate in this study patients with chronic renal failure from a specialized nephrology clinical setting. Patients will be consecutively clinically evaluated during
other
Z49.1
Sponsors
Universidade Nove de Julho - UNINOVE
Universidade Nove de Julho - UNINOVE
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with chronic renal failure candidates to renal transplant with an indication of hemodialysis, that agree to participate in the study; Both gender; Aged between 18 and 70 years; Cognitive level sufficient for understanding the prodedures and fllowing the instructions.
Exclusion criteria
Exclusion criteria: Abuse of alcohol and or drugs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease of Apnea/hypopnea index by standard overnight polysomnography.;Increase of expiratory flow as flow drop (V'), expressed as the percentage of expiratory peak flow immediately after negative expiratory pressure application. Timepoint: This will be measured after the clinical and demographic collecting data and after obstruction diagnosis by spirometry is discarded.;Increase of periodic leg movements during sleep by the standart overnight polysomnography.;Presence of anxiety and depression checked by cutoff points greater than or equal to nine by the Hospital Anxiety and Depression scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease of risk to obstructive sleep apnea through Berlin Questionnaire.;Increased stress with questionnaire Lipp Stress Symptoms Inventory for Adults.;Decrease maximal inspiratory pressure and maximal expiratory pressure evaluated by digital manuvacuometer.;Increase the sleep physiological variables, total sleep time and, sleep latency and, sleep stages and, behavior disturbes assessed by the standart overnight polysomnograph.;Increased simpathetic and decreased parassimpathetic autonomic nervous activity by heart rate variability analysis.;Decrease the neck circunference in centimeters.;Increase of quality of life assessment through the SF36 quality of life questionnaire.;Decrease diurnal excessive assessed sleepiness by the Epworth Sleepiness Scale. | — |
Countries
Brazil
Contacts
Public ContactLuís Vicente;Luís Oliveira;Oliveira
Universidade Nove de Julho - UNINOVE;Universidade Nove de Julho - UNINOVE
Outcome results
None listed