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Clinical evaluation in humans of alveolar bone preservation after filling by bovine composite bone substitute

Evaluation of the maintenance of alveolar bone volume in humans, after filling with bone composite of bovine origin, clinical evaluation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7ybwkm
Enrollment
Unknown
Registered
2018-03-02
Start date
2011-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Root caries, tooth fractures, alveolar bone loss.

Interventions

This study was conducted in 40 healthy patients, ASA I surgical risk, requiring single-tooth extraction without periapical lesion or periodontal disease and preserved alveolus with 5 walls. After the
Procedure/surgery
E06.892

Sponsors

Faculdade de Odontologia de Araçatuba - UNESP
Lead Sponsor
Centro de Pesquisas São Leopoldo Mandic
Collaborator

Eligibility

Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Healthy patients, surgical risk ASA I; requiring extraction of a single uniradicualar tooth for posterior placement of osseointegrated implant; without periapical lesion; or periodontal disease; and preserved alveolus with 5 wall after the surgical procedure of tooth extraction.

Exclusion criteria

Exclusion criteria: Patients with incompatible age established by the study; patients with systemic diseases; smoking patients; patients with periodontal disease or periapical lesion; and patients who after the exodontia procedure did not present the alveolus preserved with 5 walls.

Design outcomes

Primary

MeasureTime frame
Difference of the linear measurements of the dental alveolus in the act of the tooth extraction (fresh socket) and after 4 months of alveolar healing. The level of alveolar remodeling was measured in percentage after 4 months of the tooth extraction.;It was observed smaller differences of the linear measurements of the alveolus in the periods of the fresh alveolus and after 4 months of alveolar repair in the biomaterial group. These differences of the linear measurements were converted into percentage and it was possible to observe that the biomaterial preserves the level of alveolar remodeling 4 months after the tooth extraction procedure.

Secondary

MeasureTime frame
The level of remodeling in percentage was measured by linear measures in millimeters at the initial period and after 4 months of alveolar healing.;A lower level of alveolar bone remodeling was observed when the biomaterial was grafted inside the alveolus in comparison to the control group.

Countries

Brazil

Contacts

Public ContactVail Júnior

Centro de Pesquisas São Leopoldo Mandic

vailnatalejr@gmail.com+55 19 38692750

Outcome results

None listed

Source: REBEC (via WHO ICTRP)