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Effect of strength training on body composition, biochemical markers and quality of life in patients with chronic kidney disease

Effect of strength training in patients with chronic kidney disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7xmh8d
Enrollment
Unknown
Registered
2020-03-26
Start date
2019-04-08
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease, Hemodialysis

Interventions

This is a quasi-experimental study. In this type of design, there is no random distribution of subjects by treatments, nor a control group, all patients undergo a training program serving as their own
functional capacity was assessed using the 30-second sit and stand test, the lipid profile, through tests of total cholesterol and its fractions, low and high density lipoprotein (LDL AND HDL) and tri
quality of life was analyzed using the questionnaire Kidney disease and quality of life (KDQOL SF-36).
Other
C05.116.198.816.750

Sponsors

Universidade do estado do rio grande do norte
Lead Sponsor
Universidade do estado do rio grande do norte
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients of both sexes aged 18 to 65 years, undergoing HD treatment with a minimum time of three months, with vascular access by arteriovenous fistula, with independent ambulation. All participants responded to an anamnesis prior to study initiation.

Exclusion criteria

Exclusion criteria: Patients who were engaged in an exercise program, with physical disability and musculoskeletal limitations that precluded assessments and exercise protocol, with a history of heart attack in the last six months, with recent hospitalization history (<3 months), decompensated diabetes and blood pressure, pregnant , pacemaker users and with less than 70% attendance of training sessions.

Design outcomes

Primary

MeasureTime frame
The assessment of functional capacity was performed using the sit-and-stand test (TSL) for 30 seconds. For its realization, a chair without support for upper limbs was used, with seat height of 43.2 cm. The chair was placed against the wall to prevent it from moving during the test, thereby avoiding any unforeseen events. The test started with the participants seated, their backs straight, feet approximately shoulder-width apart and arms close to the chest. When the initial “go” signal was given, the participant stood and then returned to his original sitting position. Participants were encouraged to complete as many repetitions as possible for a period of 30s. Before starting the test, a practical test of repetition for familiarization was performed, followed by the test. The score was the total number of repetitions performed correctly in 30 seconds, with repetitions performed incorrectly not counted.

Secondary

MeasureTime frame
Body composition measures (total body fat, trunk, leg, arm, lean mass, fat mass, android and gynoid) were evaluated using the Dual Energy X-ray Absorptiometry (DEXA) Dual Energy X-ray Absorptometry technique, using equipment Lunar Prodigy Advance from General Electric Company ©, with effective radiation emission of 1 to 5 ?Gy (Micro Grays) per exam, equivalent to natural radiation of = 5 to 8 ?Gy. The evaluation took place with the subject lying in the supine position, wearing light clothes without metal parts, as well as props (watch, earrings, rings, etc.) and barefoot, centered on the equipment platform, within the scanned area, with arms outstretched along the body, hands open, palms facing the body, thumb up and legs were immobilized with a velcro band. To perform the exam, the following recommendations were followed: fasting of food and water in the previous two hours, and not performing physical activity in the previous 24 hours. In relation to the equipment, it was previously calibrated before any analysis and, afterwards, information regarding weight, height and age was inserted in the software.;From the blood samples of the patients, monthly collected total cholesterol (TC) triglycerides (TG), high and low density lipoproteins (HDL-C and LDL-C) were analyzed using the enzymatic colorimetric method according to the specifications of the manufacturer of Roche automated equipment (Hitachi 917 automated, Switzerland);The quality of life assessment was performed using the Kidney Disease and Quality of Life - Short Form (KDQOL SF-36) instrument, which quantitatively assesses the patients' level of quality of life, previously translated, validated and adapted. This instrument includes the SF-36 (Short Form - 36 Item Health Survey), which is an instrument for the general assessment of QOL, plus 43 DRC items. The SF-36 is composed of 36 items, divided into eight dimensions: physical functioning (10 items); limitations caused by physical health problems (four items)

Countries

Brazil

Contacts

Public ContactSilvana Araújo

Universidade do Estado do Rio Grande do Norte

silvanamedeiros87@hotmail.com+5584998171947

Outcome results

None listed

Source: REBEC (via WHO ICTRP)