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Clinical, microbiological and immunological adjunctive effect of photodinamyc therapy in periodontal maintenance therapy.

Clinical, microbiological and immunological adjunctive effect of photodinamyc therapy in residual periodontal pockets in periodontal maintenance therapy: a split-mouth randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-7x22bcc
Enrollment
Unknown
Registered
2022-11-07
Start date
2022-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis. Gingivitis

Interventions

In this randomized, controlled clinical trial with a split-mouth design, 24 subjects undergoing periodontal maintenance will receive in periodontal pockets equal to or greater than 4mm scaling and roo
E02.186.500

Sponsors

Universidade Federal de Minas Gerais
Lead Sponsor
Universidade de Taubaté
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Present at least one appointment for periodontal maintenance therapy in the 12-month interval; bilateral presence of greater equal 2 interproximal sites with a probing depth greater equal 5 mm; clinical attachment levels greater equal 4mm and presence of bleeding on probing (not same tooth)

Exclusion criteria

Exclusion criteria: Patients who were absent from maintenance therapy for more than 12 months. diabetics; former/ somoking; antibiotic use for any purpose within 3 months prior to entering the study; pregnancy and/or lactating women

Design outcomes

Primary

MeasureTime frame
To assess whether there was an increase in the level of clinical periodontal attachment in residual periodontal pockets treated with additional photodynamic therapy (aPDT).

Secondary

MeasureTime frame
Obtain greater reduction in the levels of periodontopathogens and cytokines in the test group (additional treatment with PDT) compared to the control group (placebo) by means of real-time PCR or ELISA.

Countries

Brazil

Contacts

Public ContactFernando Costa

Universidade Federal de Minas Gerais

focperio@uol.com.br+55(31)34092427

Outcome results

None listed

Source: REBEC (via WHO ICTRP)