Myalgia
Conditions
Interventions
The effect of prophylactic treatment with the hesperidin-derived flavonoid of the chalcone class, Heperidine Methyl Chalcone (five hundred milligrams orally
for three days, one capsule a day
sample of 15 participants) will be tested. The control group will be treated with placebo (corn starch, five hundred milligrams orally, for three days, one capsule a day, sample of 15 participants). T
D03.383.663.283.266.450
Sponsors
Universidade Norte do Paraná
Universidade Norte do Paraná
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Male; age between 18 and 45 years old; and to be able to develop the proposed exercise-induced muscle pain model.
Exclusion criteria
Exclusion criteria: Musculoskeletal and/or neurological lower limby injuries diagnosed at the time of screening; chronic use of anti-inflammatory, antidepressant and/or analgesic drugs will be considered an exclusion factor (considering that they may interfere in the analysis of some parameters that will be evaluated in the study, such as muscle pain and production of cytokines and other biological markers); calorie-restricted diet; and ergogenic supplementation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected reduction of exercise-induced muscle soreness (DOMS). Subjective muscle pain will be evaluated using a visual analogue scale (VAS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Will be evaluated the systemic production of inflammatory markers (cytokines), by ELISA (enzyme-linked immunosorbent assay); performance improvement (muscular capacity recovery), evaluated through maximum voluntary isometric contraction (extension chair) and vertical jump power (strength platform); and improved postural balance (balance platform). | — |
Countries
Brazil
Contacts
Public ContactSergio Borghi
Universidade Norte do Paraná
Outcome results
None listed