Sarcopenia
Conditions
Interventions
The experimental group: 14 participants of both sexes, assisted by the Home Care - AD classified as AD1, AD2 or AD3 called Supplemented Group - GS, will receive 4 weeks of supplement Coenzyme Q10 100m
G07.203.300.456
Sponsors
Priscila Evangelista de Melo
Universidade De Franca
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Volunteers of both genders should be included in the present study; age over 18 with no maximum age limit; who are in the process of illness in rehabilitation; or in oncological palliative care; or in non-cancer palliative care; in any AD1 home care classification; AD2 or AD3; when they are in palliative care, they should be classified by the Palliative Performance Scale from 20% onwards; able to answer fatigue questionnaires; able to answer the quality of life questionnaire proposed in this study; with trunk control that allows sitting; ability to perform the physical strength test using a dynamometer
Exclusion criteria
Exclusion criteria: Volunteers under 18 years of age should be excluded from the present study; in terminal stage of life; insanity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outcome 1: As an outcome on muscle strength capacity, it was possible to observe in the group supplemented (GS) with 100 milligrams per day of Coenzyme Q10 (CoQ10), an increase in strength capacity after 4 weeks, with evolution until the end of the trial clinical 8 weeks. Suggesting that there is a favorable effect of CoQ10 in relation to strength gain, after a short period of supplementation with CoQ10, remaining over time.;Expected outcome 2: As an outcome on nutritional status, it is expected to observe weight maintenance or gain. Nutritional intervention and supplementation will be performed for 8 weeks. For evaluation, weight and height will be measured with the aid of a digital scale for weight measurement, and a stadiometer for height measurement. When it is not possible to perform anthropometry on a scale and stadiometer, measurement of arm circumference and knee height will be performed to estimate weight and height through equations. At the end the 3 results will be observed. to calculate BMI before, after 4 weeks (4S) and after 8 weeks (8S) of the nutritional intervention and supplementation with CoQ10, called PRE, 4S and 8S periods, respectively. For comparison of results. The eating habits will be evaluated through a food frequency record applied during nutritional care and then a food menu will be proposed according to the patient's routine, the nutritional composition will be standardized at 25 kilocalories per kilogram of weight, 1.5 g of protein per kilogram of weight and 30 to 50 milliliters of water per kilogram of weight, in addition to nutritional guidelines.;Outcome 2: As an outcome on nutritional status, it was possible to observe maintenance in the weight of participants in both the placebo and supplemented groups. Demonstrating that the immediate and effective nutritional intervention was efficient to maintain the nutritional condition of the participants. Possibly, CoQ10 does not interfere with weight loss or weight gain in sick individuals | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 4: as an outcome on quality of life, it is expected to observe positive changes in the perception of quality of life. The instrument used for evaluation is the Measuring Quality of Life The World Health Organization breaf questionnaire (WHOQOL – breaf) applied before the nutritional intervention and supplementation with CoQ10, called (PRE) and after 8 weeks (8S) of nutritional intervention and supplementation with CoQ10 , called period (8S). For comparison of results.;Outcome 4: as an outcome on quality of life, it was possible to observe that there was an improvement in the perception of quality of life among individuals in the Supplemented Group (SG) at the end of the experiment. This suggests that CoQ10 has a positive effect on the perception of quality of life. | — |
Countries
Brazil
Contacts
Public ContactServiço de Atenção Domiciliar Secretaria Municipal de Saúde Patos de Minas
Prefeitura Municipal de Patos de Minas
Outcome results
None listed