Obstructive Sleep Apnea
Conditions
Interventions
Randomized double blind controlled cross-over clinical trial, with four parallel arms. 36 patients divided into four arms will be included. In group A 9 patients will be randomized to start treatment
D03.383.533.640.682
D27.505.519.625.120.200
Sponsors
Departamento de Cirurgia da Universidade Federal do Rio Grande do Norte
Departamento de Cirurgia da Universidade Federal do Rio Grande do Norte
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients aged 18 years or older diagnosed; both genders; with Obstructive Sleep Apnea according to the criteria of the American Academy of Sleep Medicine (AASM).
Exclusion criteria
Exclusion criteria: Pregnant patients; cognitive disorders that prevent understanding to provide consent and adequate use of proposed therapies; use of medications or drugs that have a known interaction with the proposed therapy; allergy to any of the components of the proposed therapies; angle-closure glaucoma; partial or total obstruction of the gastrointestinal tract; paralytic ileus; intestinal atony in the elderly; megacolon; toxic megacolon; complication of ulcerative colitis; severe colitis; myasthenia gravis; unstable cardiovascular status due to acute hemorrhage; obstructive uropathy or urinary retention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the difference in the Apnea-Hypoapnea Index (AHI) between patients in the intervention group and control groups using polysomnography using the AHI | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess daytime sleepiness using the Epworth sleepiness scale, quality of life using the FOSQ-10 questionnaire, and minimum saturation using polysomnography. | — |
Countries
Brazil
Contacts
Public ContactMaria Nobre
Departamento de Cirurgia da Universidade Federal do Rio Grande do Norte
Outcome results
None listed