melanosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Woman; bilateral facial melasma; over 18 years old; user of SPF 50 sunscreen every 4 hours
Exclusion criteria
Exclusion criteria: Patients under 18 years of age; pregnant and lactating women; patients on any therapy with warfarin, heparin, aspirin or any other anticoagulant medication; patients on vitamin E therapy; patient on hormone replacement therapy or photosensitizing drugs such as tetracycline, spironolactone , phenytoin and carbamazepine; patient with hypersensitivity to the formulations used in the study; patients with bleeding disorders; patient with skin changes such as facial warts, active/recurrent herpes simplex, dermatitis and/or seborrheic, atopic and eczematous dermatosis; patient with a history of keloids or hypertrophic scars; immunocompromised patients; oncology patients; patients with a history of use of oral or topical retinoids, oral tranexamic acid, dermabrasion, laser, surgery, topical bleaching agents, chemical peels performed on the face in the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a better depigmenting effect on the side of the face treated with the peeling evaluated by the peeling and MAsi scale | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are expected. | — |
Countries
Brazil
Contacts
Universidade Estadual de Ponta Grossa