Periodontitis
Conditions
Interventions
An open-label, two-arm randomized clinical trial will be conducted. Fifty kidney transplant recipients followed at the Pedro Ernesto University Hospital will be allocated to either the test group (n =
Sponsors
Faculdade de odontologia da UERJ
Faculdade de odontologia da UERJ
Eligibility
Inclusion criteria
Inclusion criteria: Kidney transplant patients seeking care at Pedro Ernesto University Hospital; Patients diagnosed with Stage III and IV periodontitis; Patients must have at least 8 teeth in the mouth (excluding third molars);Patients eligible to undergo periodontal treatment without the need for antibiotic prophylaxis; individuals of both sexes and all age groups
Exclusion criteria
Exclusion criteria: Periodontally healthy patients; patients diagnosed with mild periodontitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A reduction in systemic inflammatory markers is expected following periodontal therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected an improvement in periodontal clinical parameters (probing depth, clinical attachment level, bleeding on probing, plaque index, and periodontal inflamed surface area); Improvement in renal function and systemic inflammation biomarkers (proteinuria, ADMA, SDMA, and cystatin C) | — |
Countries
BR
Contacts
Public ContactLívia Neves
School of Dentistry, State University of Rio de Janeiro (UERJ)
Outcome results
None listed