Sepsis, endothelium, autonomic nervous system, inflammation
Conditions
Interventions
Passive mobilization group: 15 unconscious patients will receive the protocol of passive mobilization exercises only once. Active mobilization group: 15 conscious patients will receive the protocol of
Other
E02.760.169.063.500.387
E02.760.169.063.500
Sponsors
Centro de Ciências Biológicas e da Saúde da Universidade Federal de São Carlos
Centro de Ciências Biológicas e da Saúde da Universidade Federal de São Carlos
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Clinical diagnosis of sepsis.
Exclusion criteria
Exclusion criteria: atrial fibrillation;pre-existing atrioventricular block or ventricular tachycardia; recent myocardial infarction (<6 months);patients with pacemaker; stroke; signs of intracranial hypertension; cranioencephalic trauma; neuromuscular disease; Body mass index (BMI) greater than 40; patient with neoplasia undergoing chemotherapy and unconsolidated fracture.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in endothelial function, verified by the measurement of vasodilatation mediated by the flow of the brachial artery (FMD) from the difference between basal diameter and hyperemia diameter in percentage. | — |
Secondary
| Measure | Time frame |
|---|---|
| Increase in cardiac modulation, assessed by increasing heart rate variability (HRV) and their variables, increse in mean RR (mean RR), standard deviation of the mean of all RR-R (STDRR), and square root mean squares of the differences between successive iR-Rs (rMSSD), low frequency indexes - BF and high frequency - AF, in standard units and BF / AF ratio. | — |
Countries
Brazil
Contacts
Public ContactRenata Mendes
Universidade Federal de São Carlos
Outcome results
None listed